TITLE

Another genotoxic agent released by mitochondrial meltdown

AUTHOR(S)
Knight, R A; Petit, P X
PUB. DATE
December 2001
SOURCE
Cell Death & Differentiation;Dec2001, Vol. 8 Issue 12, p1134
SOURCE TYPE
Academic Journal
DOC. TYPE
Editorial
ABSTRACT
Editorial. Looks at the probable role of endonuclease G, a protein of the pro-apoptotic family, in causing cell death. Effect of mitochondrial damage in the dysregulation of its ancestral toxin/antitoxin component with consequent cell death; Involvement of endonuclease G in nuclear DNA disagregation; Need to know whether endonuclease G can cause death by itself.
ACCESSION #
8851243

 

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