TITLE

[18F]FLT; portrait of a proliferation marker

AUTHOR(S)
Mier, W.; Haberkorn, U.; Eisenhut, M.
PUB. DATE
February 2002
SOURCE
European Journal of Nuclear Medicine & Molecular Imaging;2002, Vol. 29 Issue 2, p165
SOURCE TYPE
Academic Journal
DOC. TYPE
Editorial
ABSTRACT
Editorial. Examines the antiviral properties of the chemical, fluorothymidine (FLT). Salvage pathways of nucleosides dependent on the tandem operation of facilitated transport; Rate of metabolism, trapping and excretion; Congruence in the uptake of the chemical found in two human and murine tumor cell lines.
ACCESSION #
6294647

Tags: ANTIVIRAL agents;  VIRUS inhibitors

 

Related Articles

  • HAART Makes Casual Drug Use More Dangerous.  // Men's Fitness;May2003, Vol. 19 Issue 5, p60 

    Reports on the dangerous effects of the casual use of highly active antiretroviral therapy drugs.

  • Phase 2 Study of the Safety and Efficacy of Vicriviroc, a CCR5 Inhibitor, in HIV-1-Infected, Treatment-Experienced Patients: AIDS Clinical Trials Group 5211. Gulick, Roy M.; Zhaohui Su; Flexner, Charles; Hughes, Michael D.; Skolnik, Paul R.; Wilkin, Timothy J.; Gross, Robert; Krambrink, Amy; Coakley, Eoin; Greaves, Wayne L.; Zolopa, Andrew; Reichman, Richard; Godfrey, Catherine; Hirsch, Martin; Kuritzkes, Daniel R. // Journal of Infectious Diseases;7/15/2007, Vol. 196 Issue 2, p304 

    Background. Vicriviroc, an investigational CCR5 inhibitor, demonstrated short-term antiretroviral activity in a phase 1 study. Methods. The present study was a double-blind, randomized phase 2 study of vicriviroc in treatment-experienced, human immunodeficiency virus (HIV)-infected subjects...

  • Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity. Shin-Ru Shih; Tzu-Yun Chu; Reddy, Gadarla Randheer; Sung-Nain Tseng; Hsiun-Ling Chen; Wen-Fang Tang; Ming-sian Wu; Jiann-Yih Yeh; Yu-Sheng Chao; Hsu, John T. A.; Hsing-Pang Hsieh; Jim-Tong Horng // Journal of Biomedical Science;2010, Vol. 17, p1 

    Background: Influenza viruses are a major cause of morbidity and mortality around the world. More recently, a swine-origin influenza A (H1N1) virus that is spreading via human-to-human transmission has become a serious public concern. Although vaccination is the primary strategy for preventing...

  • Human T Cell Lymphotropic Virus (HTLV) Type-1-Specific CD8+ T Cells: Frequency and Immunodominance Hierarchy. Goon, Peter K. C.; Biancardi, Mix; Fast, Noam; Igakura, Tadahiko; Hanon, Emmanuel; Mosley, Angelina J.; Asquith, Becca; Gould, Keith G.; Marshall, Sara; Taylor, Graham P.; Bangham, Charles R. M. // Journal of Infectious Diseases;6/15/2004, Vol. 189 Issue 12, p2294 

    Human T cell lymphotropic virus type 1 (HTLV-1) causes HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). We used interferon-? enzyme-linked immunospot assays with overlapping peptides spanning the entire HTLV-1 proteome to test whether the HTLV-1-specific CD8+ T cells differed...

  • Increased Antiviral Medication Sales Before the 2005-06 Influenza Season -- New York City. Miller, J.; Schmit, K.; Duncan, P.; Waters, C.; Johnson, G.; Chang, H.; Wallace, B.; Kacica, M.; Smith, P.; Das, D.; Harper, S.; Heffernan, R.; Olson, D.; Nivin, B.; Weiss, D. // MMWR: Morbidity & Mortality Weekly Report;3/17/2006, Vol. 55 Issue 10, p277 

    Provides information on a study which examined antiviral medication sales before the 2005-2006 influenza season in New York City. List of antiviral medications approved for the treatment and/or prophylaxis of influenza A and/or B; Methodology of the study; Findings of the study.

  • Antiviral Drug Discovery Against SARS-CoV. Yu-Shan Wu; Wen-Hsing Lin; Hsu, John T.-A.; Hsing-Pang Hsieh // Current Medicinal Chemistry;2006, Vol. 13 Issue 17, p2003 

    Severe Acute Respiratory Syndrome (SARS) is a life-threatening infectious disease caused by SARSCoV. In the 2003 outbreak, it infected more than 8,000 people worldwide and claimed the lives of more than 900 victims. The high mortality rate resulted, at least in part, from the absence of...

  • Cessation of HIV-1 Transcription by Inhibiting Regulatory Protein Rev-Mediated RNA Transport. Yuan Cao; Xinyong Liu; De Clercq, Erik // Current HIV Research;Jan2009, Vol. 7 Issue 1, p101 

    The HIV-1 Rev protein, which traffics through nucleolus and shuttles between nucleus and cytoplasm, facilitates export of unspliced and singly spliced viral transcripts containing RRE RNA by the CRM1 export pathway. Inhibitions of the various stages of Rev-mediated RNA transport can arrest HIV-1...

  • Antiviral Management of Seasonal and Pandemic Influenza. Hayden, Frederick G.; Pavia, Andrew T. // Journal of Infectious Diseases;11/2/2006, Vol. 194, pS119 

    The goals of antiviral treatment for influenza are to decrease symptoms and functional disability and, more important, to decrease associated complications, hospitalizations, and mortality. Four drugs have been approved for treatment of and prophylaxis against influenza in the United States, but...

  • Long-term clinical and surrogate marker effects of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients. C. Herzmann; Z. Cuthbertson; L. Fosdick; M. Fisher; M. Nelson; N. Perry; M. Law; H. Wand; G. Janossy; M. A. Johnson; M. Youle // Journal of Antimicrobial Chemotherapy (JAC);Sep2008, Vol. 62 Issue 3, p583 

    : Objectives Subcutaneous administration of interleukin-2 (IL-2) has been shown to increase CD4 counts in HIV-infected patients. It remains unclear whether this effect is associated with a clinical benefit. : Patients and methods We conducted a long-term follow-up in the cohort of the...

Share

Read the Article

Courtesy of your local library

Public Libraries Near You (See All)
Looking for a Different Library?

Other Topics