The Question Is, My Dear Watson, Why Did the Dog Not Bark?

April 2011
Diabetes Care;Apr2011, Vol. 34 Issue 4, p1060
Academic Journal
The author focuses on the Joslin 50-Year Medalist Study and examines the factors protecting the study subjects against complications. He offers an overview of the surviving Joslin Gold Medalists who came from the U.S. He discusses the application of metabolic memory in diabetes and cites some of the major mechanisms contributing to bad metabolic memory such as glucotoxicity, hexosamine and accumulation of advanced glycation end product (AGE).


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