The genetics of prostate cancer

Rafnar, Thorunn; Sulem, Patrick; Gudmundsson, Julius
September 2010
Romanian Journal of Urology;Sep2010, Vol. 9 Issue 3, p5
Academic Journal
Prostate cancer is the most common incident cancer and the third most common cause of cancer related mortality in males in Europe, with over 89,000 deaths estimated in the year 2008 (9.3% of all cancer deaths in males). Apart from age, the strongest risk factor for prostate cancer is family history of the disease, highlighting the importance of genetics in disease development. Recently, considerable progress has been achieved in the identification of genetic factors that associate with prostate cancer risk, raising hopes that this knowledge may be used both to gain insights into the pathogenesis of the disease and to develop tools for risk assessment.


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