TITLE

Editorial: Neurolysis for Pancreatic Cancer Pain: Same Song, Different Verse?

AUTHOR(S)
Virtue, Mark A.; Levy, Michael J.
PUB. DATE
December 2010
SOURCE
American Journal of Gastroenterology;Dec2010, Vol. 105 Issue 12, p2607
SOURCE TYPE
Academic Journal
DOC. TYPE
Editorial
ABSTRACT
Abstract: Since Kappis first performed percutaneous neurolysis in 1914, investigators have employed innumerable technical variations in an effort to enhance the efficacy. Similar efforts have been underway by endosonographers since Wiersema performed the first endoscopic ultrasound (EUS)-guided celiac plexus neurolysis in 1996. Although such efforts are important, the availability of multiple procedural options is indicative of the controversy and lack of meaningful progress. If one particular method was clearly superior, the other techniques would have become obsolete. Sakamoto et al. present a new method of EUS-guided neurolysis in an attempt to improve the outcomes. Although their data are promising, we eagerly await rigorously designed studies that may validate their findings.
ACCESSION #
55595918

 

Related Articles

  • Numerical study on microbubble-enhanced heating for various parameters in EUS-FUS. Okita, Kohei; Maezawa, Miyuki; Takagi, Shu; Matsumoto, Yoichiro // AIP Conference Proceedings;Nov2012, Vol. 1503 Issue 1, p71 

    Endoscopic ultrasonography guided focused ultrasound surgery (EUS-FUS) have been developed as a less-invasive treatment for pancreatic cancer. In the present study, microbubble-enhanced heating for various parameters in EUS-FUS is investigated numerically. Mass and momentum equations for bubbly...

  • Phase 1/2a, dose-escalation, safety, pharmacokinetic and preliminary efficacy study of intratumoral administration of BC-819 in patients with unresectable pancreatic cancer. Hanna, N; Ohana, P; Konikoff, F M; Leichtmann, G; Hubert, A; Appelbaum, L; Kopelman, Y; Czerniak, A; Hochberg, A // Cancer Gene Therapy;Jun2012, Vol. 19 Issue 6, p374 

    BC-819 is a DNA plasmid that was developed to target the expression of diphtheria-toxin gene under the control of H19 regulatory sequences. BC-819 has the potential to treat pancreatic cancer that overexpresses the H19 gene. The objectives were to assess the safety, tolerability,...

  • Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Solid Pancreatic Lesions at a Tertiary Referral Center will Alter the Initial Inconclusive Result. Suzuki, Rei; Lee, Jeffrey H.; Gopala Krishna, Somashekar; Ramireddy, Srinivas; Wei Qiao; Weston, Brian; Ross, William A.; Bhutani, Manoop S. // Journal of Gastrointestinal & Liver Diseases;Jun2013, Vol. 22 Issue 2, p183 

    Background & Aims: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is indispensable for the diagnosis of solid pancreatic lesions (SPLs). However, initial attempt of EUS-FNA can be inconclusive. We retrospectively evaluated the ability of repeat EUS-FNA at a tertiary referral...

  • Diagnostic Management of Pancreatic Cancer. Dabizzi, Emanuele; Assef, Mauricio Saab; Raimondo, Massimo // Cancers;2011, Vol. 3 Issue 1, p494 

    Pancreatic cancer is one of the most deadly solid tumors, with an overall 5-year survival rate of less than 5%. Due to a non-specific clinical presentation, it is often diagnosed at an advanced stage and is rarely amenable for curative treatment. Therefore early diagnosis and appropriate staging...

  • Preoperative endoscopic ultrasound-guided fine needle aspiration does not impair survival of patients with resected pancreatic cancer. Ngamruengphong, Saowanee; Swanson, Kristi M.; Shah, Nilay D.; Wallace, Michael B. // Gut;Jul2015, Vol. 64 Issue 7, p1105 

    Objective Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) allows preoperative tissue confirmation of malignancy, but fear of tumour cell dissemination along the needle track has limited its use. We hypothesised that if tumour cell dissemination occurs with EUS-FNA, survival after...

  • Rapid On-Site Evaluation Reduces Needle Passes in Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Solid Pancreatic Lesions: A Risk-Benefit Analysis. Schmidt, Robert; Walker, Brandon; Howard, Kirsten; Layfield, Lester; Adler, Douglas // Digestive Diseases & Sciences;Nov2013, Vol. 58 Issue 11, p3280 

    Background: The effectiveness of endoscopic ultrasound-guided fine-needle aspiration increases with the number of needle passes but needle passes are also associated with increased risk of adverse events. The trade-off between needle passes and adequacy has not been well-characterized. Aims: The...

  • Diagnosis and management of pancreatic cancer. Kanji, Zaheer S.; Gallinger, Steven // CMAJ: Canadian Medical Association Journal;10/1/2013, Vol. 185 Issue 14, p1219 

    The article discusses issues related to the diagnosis and management of pancreatic cancer. The risk factors of pancreatic cancer are active smoking and a family history of pancreatic cancer. Screening involves the use of a combination of endoscopic ultrasound, computed tomography (CT) imaging,...

  • Balanced Propofol Sedation Versus Propofol Monosedation in Therapeutic Pancreaticobiliary Endoscopic Procedures. Lee, Tae; Lee, Chang; Park, Sang-Heum; Lee, Suck-Ho; Chung, Il-Kwun; Choi, Hyun; Cha, Sang; Moon, Jong; Cho, Young; Hwangbo, Young; Kim, Sun-Joo // Digestive Diseases & Sciences;Aug2012, Vol. 57 Issue 8, p2113 

    Background: Prolonged or complex endoscopic procedures are frequently performed under deep sedation. However, no studies of therapeutic ERCP have yet compared the use of balanced propofol sedation (BPS) to propofol alone, titrated to moderate levels of sedation. Aim: This prospective,...

  • Therapeutic Endoscopic Ultrasonography: Intratumoral Injection for Pancreatic Adenocarcinoma. Shirley, Lawrence A.; Aguilar, Laura K.; Aguilar-Cordova, Estuardo; Bloomston, Mark; Walker, Jon P. // Gastroenterology Research & Practice;2013, p1 

    Pancreatic adenocarcinoma is an aggressive disease that has poor outcomes despite maximal traditional therapies. Thus, treatment of this cancer demands innovative strategies to be used in addition to standing therapies in order to provide new avenues of care. Here, we describe the technique of...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics