Understanding the relevance of sample size calculation

Nayak, Barun Kumar
November 2010
Indian Journal of Ophthalmology;Nov2010, Vol. 58 Issue 6, p469
Academic Journal
The author reflects on the need for sample size calculation before conducting a study. He states that an appropriate sample size leads to accurate and precise conclusion of a study. He notes that a small sample size may lead to a false negative conclusion or type II error, which can be beneficial in meta-analysis. He discusses several factors to be considered in sample size, such as the effect size. The author adds that mistakes on sample size calculation affect the value and power of a study.


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