Hypoglycemia in the Critically Ill: How Low Is Too Low?

Krinsley, James S.; Keegan, Mark T.
March 2010
Mayo Clinic Proceedings;Mar2010, Vol. 85 Issue 3, p215
Academic Journal
The authors reflect on a study on hypoglycemia in the critically ill conducted by M. Egi and colleagues. They cite the strengths of the study, which include the use of the glucose oxidase method for all glucose measurements, the avoidance of analytic inconsistencies associated with the application of point-of-care devices and the usage of time-weighted glucose concentrations. They conclude that the study confirms the effects of hypoglycemia.


Related Articles

  • Strict versus moderate glucose control after resuscitation from ventricular fibrillation. Oksanen, Tuomas; Skrifvars, Markus B.; Varpula, Tero; Kuitunen, Anne; Pettilä, Ville; Nurmi, Jouni; Castrén, Maaret; Pettilä, Ville; Castrén, Maaret // Intensive Care Medicine;Dec2007, Vol. 33 Issue 12, p2093 

    Objective: Elevated blood glucose is associated with poor outcome in patients resuscitated from out-of-hospital cardiac arrest (OHCA). Our aim was to determine whether strict glucose control with intensive insulin treatment improves outcome of OHCA patients.Design: A...

  • Relationship between the tricuspid annular plane systolic excursion and right and left ventricular function in critically ill patients. Lamia, Bouchra; Teboul, Jean-Louis; Monnet, Xavier; Richard, Christian; Chemla, Denis // Intensive Care Medicine;Dec2007, Vol. 33 Issue 12, p2143 

    Objective: Echocardiographic recording of the tricuspid annular plane systolic excursion (TAPSE) has been recommended for assessing right ventricular function in cardiac patients. The ability of TAPSE to reflect right ventricular function at baseline and to monitor acute changes in...

  • Abstracts from 72nd Scientific Sessions: Acute and Chronic Complications.  // Diabetes;Jun2012 Supplement, Vol. 61 Issue S1, pA549 

    Abstracts on acute and chronic complications of hypoglycemia are presented including incidence of non-severe hypoglycemia among U.S. veterans, inhaled formoterol diminishing insulin-induced hypoglycemia, and reduction of hypoglycemia in the intensive care unit (ICU).

  • Tight glycaemic control in the critically ill: losing its grip? Cain, David // British Journal of Hospital Medicine (17508460);Apr2010, Vol. 71 Issue 4, p237 

    The article discusses the hypoglycaemia occurrence in critically ill situation, several ways to control it, and its effects on human body. It states that it can be controlled by administering insulin for targeting blood sugar concentration. It further states tat their have been a lack of...

  • Gastric feed intolerance is not increased in critically ill patients with type II diabetes mellitus. Nguyen, N. Q.; Lam, S. W.; Ching, K.; Chapman, M.; Fraser, R. J.; Holloway, R. H. // Intensive Care Medicine;Oct2007, Vol. 33 Issue 10, p1740 

    To examine the occurrence of feed intolerance in critically ill patients with previously diagnosed type II diabetes mellitus (DM) who received prolonged gastric feeding. Retrospective study in a level 3 mixed ICU. All mechanically ventilated, enterally fed patients ( n = 649), with ( n = 118)...

  • Intensive insulin therapy reduced the incidence of neurologic complications in critically ill patients: COMMETARY. Bleck, Thomas P. // ACP Journal Club;Jan/Feb2006, Vol. 144 Issue 1, p20 

    This article comments on a study conducted to examine the efficacy of intensive insulin therapy in reducing the incidence of neurologic complications in critically ill patients. In a surgical intensive care unit (ICU) population, intensive insulin therapy decreased mortality, bloodstream...

  • Ask the Experts. Byrum, Diane // Critical Care Nurse;Apr2004, Vol. 24 Issue 2, p86 

    Stresses the need to treat hyperglycemia in critically ill patients. Description of hyperglycemia; Impact of hyperglycemia on critically ill patients; Reference to several studies about hyperglycemia.

  • Comparative effects on glucose absorption of intragastric and post-pyloric nutrient delivery in the critically ill. Di Bartolomeo, Anna E.; Chapman, Marianne J.; Zaknic, Antony V.; Summers, Matthew J.; Jones, Karen L.; Nguyen, Nam Q.; Rayner, Christopher K.; Horowitz, Michael; Deane, Adam M. // Critical Care;2012, Vol. 16 Issue 5, p11522 

    Introduction: Studies in the critically ill that evaluate intragastric and post-pyloric delivery of nutrient have yielded conflicting data. A limitation of these studies is that the influence in the route of feeding on glucose absorption and glycaemia has not been determined. Methods: In 68...

  • Second pilot trials of the STAR-Liege protocol for tight glycemic control in critically ill patients. Penning, Sophie; Le Compte, Aaron J.; Massion, Paul; Moorhead, Katherine T.; Pretty, Christopher G.; Preiser, Jean-Charles; Shaw, Geoffrey M.; Suhaimi, Fatanah; Desaive, Thomas; Chase, J. Geoffrey // BioMedical Engineering OnLine;2012, Vol. 11 Issue 1, p58 

    Background: Critically ill patients often present increased insulin resistance and stress-induced hyperglycemia. Tight glycemic control aims to reduce blood glucose (BG) levels and variability while ensuring safety from hypoglycemia. This paper presents the results of the second Belgian clinical...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics