Heat Shock Protein Expression During Cardiac Surgery

Chaudhry, Ahmad Z.; Diodato, Michael D.; Massad, Malek G.
April 2010
World Journal of Surgery;Apr2010, Vol. 34 Issue 4, p682
Academic Journal
The article discusses the role of heat shock proteins (HSP) in the inflammatory and cell-mediated responses that occur during surgery. After cardiopulmonary bypass some patients develop an inflammatory response, due to the participation of several stress related proteins by acting as chaperons. The article discusses the role and mechanism involved in the process. Better understanding of HSPs is needed to prevent cellular destabilization and complications like atrial fibrillation.


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