Can studies of harm be harmful?

Ray, Joel G.
December 2008
CMAJ: Canadian Medical Association Journal;12/2/2008, Vol. 179 Issue 12, p1243
Academic Journal
The author reflects on the study by Wen and colleagues on the use of folic acid antagonists which is associated to higher risk of placenta-mediated outcomes of pregnancy. He argues that the findings should not alter medical practice because of limited analysis of drug exposure and unreported congenital anomaly cases. He advices that even if trimethoprim-based antibiotics increase risk of placenta-mediated disease, it can be prescribed to pregnant women and those planning to get pregnant.


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