TITLE

Role of gastric atrophy in mediating negative association between Helicobacter pylon infection and reflux oesophagitis, Barrett's oesophagus and oesophageal adenocarcinoma

AUTHOR(S)
McColl, Kenneth E. L.; Watabe, Hirotsugu; Derakhshan, Mohammad H.
PUB. DATE
June 2008
SOURCE
Gut;Jun2008, Vol. 57 Issue 6, p721
SOURCE TYPE
Academic Journal
DOC. TYPE
Editorial
ABSTRACT
The author comments on the role of gastric atrophy in the negative association between Barrett's esophagus and esophageal adenocarcinoma, and Helicobacter pylori infection and reflux esophagitis. An assumption that the protective effect is due to the infection inducing gastric atrophy and is being associated with increased risk of gastric adenocarcinoma. Meanwhile, Helicobacter pylori infection does not produce detectable atrophy and protects against esophageal adenocarcinoma.
ACCESSION #
32531190

 

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