Developing the evidence for evidence-based practice
- Relighting the Inner Flame. Klotter, Jule // Townsend Letter;Jan2007, Issue 282, p72
The article discusses the significance of selective serotonin reuptake inhibitors (SSRI) in treating mental depression in the U.S. The author discusses the withdrawal effects of the drug and argues that the drugs are necessary for the patient's health. Moreover, she emphasizes the importance of...
- Selective serotonin reuptake inhibitors for unipolar depression: a systematic review of classic long-term randomized controlled trials. Deshauer, Dorian; Moher, David; Fergusson, Dean; Moher, Ester; Sampson, Margaret; Grimshaw, Jeremy // CMAJ: Canadian Medical Association Journal;5/6/2008, Vol. 178 Issue 10, p1293
Background: Selective serotonin reuptake inhibitors are increasingly used in the long-term treatment of depression. Much of the supporting evidence about the effects of these drugs comes from discontinuation trials, a variant of randomized controlled trials whose design is problematic to...
- Los antidepresivos inhibidores selectivos de recaptura de serotonina (ISRS, ISR-5HT). Chávez- León, Enrique; Patricia Ontiveros Uribe, Martha; Serrano Gómez, Carlos // Salud Mental;jul/ago2008, Vol. 31 Issue 4, p307
Depression is a frequent mental disorder in the general population. Approximately 3.7% of the population will suffer a major depressive episode throughout life. Pharmacological treatment with selective serotonin receptor inhibitors (SSRIs) is useful to treat this condition and other mental...
- Check suicide risks with SSRIs, GPs told. // Pulse;1/12/2004, Vol. 64 Issue 2, p8
Reports on a research which claims that majority of deaths from selective serotonin reuptake inhibitor occurred when patients are taking other anti-depressant drugs as well.
- Wife sneaks SSRI into her depressed husband's tea. // Pulse;1/12/2004, Vol. 64 Issue 2, p32
Offers advice to the wife of a mentally depressed man who refuses to take the selective serotonin reuptake inhibitors (SSRI) prescribed by the doctors. Reasons behind the man's refusal to take the drugs; Side-effects of SSRI; Steps that should be taken by the wife to help the husband.
- Wife sneaks SSRI into her depressed husband's tea. // Pulse;1/12/2004, Vol. 64 Issue 2, p33
Offers advice to the wife of a mentally depressed man who refuses to take the selective serotonin reuptake inhibitors (SSRI) prescribed by the doctors. Reasons behind the man's refusal to take the drugs; Side-effects of SSRI; Patient's rights issues involved in the situation.
- Selective serotonin reuptake inhibitors in depression: the influence of 5-HTTLPR and STin2 on treatment effect. Smits, Kim; Smits, Luc; Peeters, Frenk; Schouten, Jan; Janssen, Rob; Smeets, Hubert; Prins, Martin; Van Os, Jim // Annals of General Psychiatry;2006 Supplement 1, Vol. 5, pS164
A conference paper about the influence of two polymorphisms in the serotonin transporter gene, 5-HTTLPR and STin2, on selective serotonin reuptake inhibitor (SSRI) treatment outcome in major depression is presented. Results suggest that women with the 5-HTTLPR genotype and men with the STin2...
- Duloxetine: A balanced and selective norepinephrine- and serotonin-reuptake inhibitor. Westanmo, Anders D.; Gayken, Jon; Haight, Robert // American Journal of Health-System Pharmacy;12/1/2005, Vol. 62 Issue 23, p2481
Purpose. The pharmacology, pharmacokinetics, efficacy, safety, drug interactions, dosage and administration, cost, and place in therapy of duloxetine for major depression, pain from diabetic peripheral neuropathy, and stress urinary incontinence are reviewed. Summary. Duloxetine is a balanced...
- Serotonin receptors: role in depression. Artigas, F. // Actas Espanolas de Psiquiatria;ene 2008 Supplement 1, Vol. 36, p28
The article focuses on the efficacy of selective serotonin reuptake inhibitors (SSRIs) in treating mental depression. It states that serotonergic neurons are comprised of two autoreceptors which includes the raphÃ© nuclei and 5-HT axons. According to studies, the administration of SSRIs...