TITLE

Assessing the safety of drugs through observational research

AUTHOR(S)
Simpson Jr., Ross J.
PUB. DATE
February 2008
SOURCE
Heart;Feb2008, Vol. 94 Issue 2, p129
SOURCE TYPE
Academic Journal
DOC. TYPE
Editorial
ABSTRACT
The author reflects on the safety of digitalis which is the oldest drug still being used by clinicians. He pointed out that the observational research which suggests that digitalis increases mortality in patients with chronic atrial fibrillation is prone to bias because adverse outcomes are attributed to the drug and not to the clinical condition for which the drug was prescribed. He suggests that large observational studies are ideal for assessing the toxicity of digitalis.
ACCESSION #
28839646

 

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