COMMENTARY: Review: On-demand maintenance therapy with proton pump inhibitors is as effective as continuous therapy for nonerosive GERD

Mummadi, Rajasekhara R.; Pasricha, Pankaj J.
November 2007
ACP Journal Club;Nov/Dec2007, Vol. 147 Issue 3, p69
Academic Journal
The author reflects upon the findings of a study showing the on-demand maintenance therapy to be more effective than the placebo, in the treatment of patients with gastroesophageal reflux disease (GERD). He supports the heterogeneous nature of the study and considers the evasion of meta-analysis, appropriate for the study's results. He suggests the implications of the results on the pharmaceutical industry. He also comments on the controversy over the categorical or spectrum nature of the GERD.


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