α2δ ligand: a new, smart pill for visceral pain in patients with hypersensitive irritable bowel syndrome?

Camilleri, Michael
October 2007
Gut;Oct2007, Vol. 56 Issue 10, p1337
Academic Journal
The article presents the author's perspective on the concept of the heteromultimeric voltage-sensitive calcium channel. This has been involved in the function of excitable tissues including sensory nerves. The author stated that pregabalin has been shown to be effective in several animal models of inflammatory and neuropathic pain. It blocks both thermal and mechanical hyperalgesia induced by inflammatory, surgical and nerve injuries.


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