Indication creep: physician beware

Hébert, Paul C.; Stanbrook, Matthew
September 2007
CMAJ: Canadian Medical Association Journal;9/25/2007, Vol. 177 Issue 7, p697
Academic Journal
The article offers the author's comments on the off-label use of a drug called erythropoietin in the treatment of critically ill patients in the U.S. He states that the treatment may potentially result in thrombotic complications. He asserts that the treatment can be effective when physicians with understanding of the appropriate evidence, and clinical experience determine its usage. He further refers to the role of erythropoietin manufacturers in promoting widespread off-label usage.


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