Conventional antipsychotic drugs increased risk for death more than did atypical antipsychotic drugs in elderly patients: COMMENTARY
- Conventional antipsychotic drugs increased risk for death more than did atypical antipsychotic drugs in elderly patients. // ACP Journal Club;Jul/Aug2007, Vol. 147 Issue 1, p23
The article cites a research study conducted to determine whether the use of conventional or atypical antipsychotic drugs (APDs) in elderly patients is associated with increased risk for death. Multivariate analysis showed that within the first 180 days of APD therapy, the conventional group had...
- Antipsychotics in dementia raise mortality. // GP: General Practitioner;11/11/2005, p16
The article reports on an American medical research study, which has shown that atypical antipsychotics pre-scribed for dementia increase the risk of death in older patients. The researchers analyzes 15 trials including 5,510 patients with dementia who were randomized to receive either an...
- Antipsychotics increase pneumonia risk in elderly. // Reactions Weekly;4/24/2010, Issue 1298, p2
The article reports on the findings of the study "Association of Community-acquired Pneumonia with Antipsychotic Drug use in Elderly Patients: A Nested Case-control Study," by G. Trifiro et al, published in the April 6, 2010 issue of "Annals of Internal Medicine."
- Typical and atypical antipsychotic drugs and increased risk of sudden cardiac death. // Australian Journal of Pharmacy;May2009, Vol. 90 Issue 1068, p78
The article reports on the study that investigates the adjusted incidence of sudden cardiac death among users of antipsychotic drugs in Tennessee.
- Antipsychotic Agents May Lead to Increased Risk of Death for Patients With Dementia. // Journal of Gerontological Nursing;May2015, Vol. 41 Issue 5, p7
The article reports on a study published in the "Journal of the American Medical Association Psychiatry," which found that drugs intended at appeasing behavior problems of patients with dementia may also hasten their deaths.
- Both typical and atypical antipsychotic agents were associated with increased risk for sudden cardiac death. Marder, Steven; Ray, W. A. // ACP Journal Club;8/18/2009, Vol. 151 Issue 2, p10
The article reports that both typical and atypical antipsychotic drugs are associated with increased risk for sudden cardiac death. The newer atypical antipsychotic medications, as a group, are associated with risk for sudden cardiac death similar to that of older typical drugs. The comparative...
- Warnings result in switch to typical antipsychotics. // PharmacoEconomics & Outcomes News;1/9/2010, Issue 594, p5
The article discusses a study of the prescribing pattern of antipsychotic drugs for elderly patients with dementia in Italy from 2000-2005. Findings revealed that 3,991 elderly patients have antipsychotic prescription in 2005. The use of atypical antipsychotics rose from 0.2 to 9.7 per 10,000...
- Use of Clozapine in Older Asian Patients with Schizophrenia between 2001 and 2009. Xiang, Yu-Tao; Buchanan, Robert W.; Ungvari, Gabor S.; Chiu, Helen F. K.; Lai, Kelly Y. C.; Li, You-Hong; Si, Tian-Mei; Wang, Chuan-Yue; Lee, Edwin H. M.; He, Yan-Ling; Yang, Shu-Yu; Chong, Mian-Yoon; Kua, Ee-Heok; Fujii, Senta; Sim, Kang; Yong, Michael K. H.; Trivedi, Jitendra K.; Chung, Eun-Kee; Udomratn, Pichet; Chee, Kok-Yoon // PLoS ONE;Jun2013, Vol. 8 Issue 6, p1
Background: To date there has been no large-scale international study that examined the use of clozapine in older patients with schizophrenia. This study examined the use of clozapine and its demographic and clinical correlates in older patients with schizophrenia in East Asia during the period...
- Risk of Ischemic Stroke Associated with the Use of Antipsychotic Drugs in Elderly Patients: A Retrospective Cohort Study in Korea. Shin, Ju-Young; Choi, Nam-Kyong; Lee, Joongyub; Seong, Jong-Mi; Park, Mi-Ju; Lee, Shin Haeng; Park, Byung-Joo // PLoS ONE;Mar2015, Vol. 10 Issue 3, p1
Objective: Strong concerns have been raised about whether the risk of ischemic stroke differs between conventional antipsychotics (CAPs) and atypical antipsychotics (AAPs). This study compared the risk of ischemic stroke in elderly patients taking CAPs and AAPs. Method: We conducted a...