Review: Evidence from observational studies, but not randomized trials, suggests that long-term aspirin prevents colorectal cancer: COMMENTARY

Lebwohl, Benjamin; Neugut, Alfred I.
July 2007
ACP Journal Club;Jul/Aug2007, Vol. 147 Issue 1, p15
Academic Journal
The authors reflect on a study, conducted by C. Dubá and colleagues, which focuses on the effectiveness of aspirin in preventing colorectal cancer. The authors view that Dubá and colleagues highlight notable discrepancies between randomized controlled trials (RCTs) and observational studies regarding aspirin's efficacy as a chemopreventive agent. They opine that individuals prescribed aspirin or other NSAIDs for other conditions may derive a chemopreventive effect.


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