COMMENTARY: The MMRpro model accurately predicted the probability of carrying a cancer-susceptibility gene mutation for the Lynch syndrome

Terespolsky, Deborah
March 2007
ACP Journal Club;Mar/Apr2007, Vol. 146 Issue 2, p53
Academic Journal
The article presents the author's comment on the accuracy of the MMRpro model in predicting the probability of carrying a deleterious germline mutation in MMR genes MSH2, MLH1, and MSH6 for the Lynch syndrome. According to the author, the new test model MMRpro provides improved discriminatory ability over other tests and provide better performance, which heighten clinical awareness and appropriate early management of the Lynch syndrome.


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