TITLE

COMMENTARY: Microscopic-observation drug-susceptibility assay was more sensitive than standard tests for diagnosing tuberculosis

AUTHOR(S)
John, Oommen
PUB. DATE
March 2007
SOURCE
ACP Journal Club;Mar/Apr2007, Vol. 146 Issue 2, p45
SOURCE TYPE
Academic Journal
DOC. TYPE
Editorial
ABSTRACT
The article presents the author's views about a study which states that the microscopic-observation drug-susceptibility assay was more sensitive than standard tests for diagnosing tuberculosis. Sputum microscopy is the primary method for diagnosing tuberculosis in resource-limited countries where 95% of tuberculosis cases occur, but it can only detect, at best, 50% of the cases. Sputum processing and fluorescence microscopy are more sensitive than conventional direct microscopy.
ACCESSION #
24685684

 

Related Articles

  • The World Health Organization/International Union against Tuberculosis and Lung Disease Global Project on Surveillance for Anti-Tuberculosis Drug Resistance: A Model for Other Infectious Diseases. Aziz, Mohamed Abdel; Wright, Abigail // Clinical Infectious Diseases;8/15/2005 Supplement, Vol. 41, pS258 

    Tuberculosis remains a global epidemic, with one-third of the population infected and 9 million active cases. Mono- and multidrug resistance in 6 World Health Organization (WHO) regions have been assessed in 40% of the global cases diagnosed by positive results of sputum testing. The 2004 report...

  • Simple low-cost test for drug-resistant tuberculosis. Toma, Tudor // Bulletin of the World Health Organization;2000, Vol. 78 Issue 11, p1370 

    Reports on the development of a test kit used to identify Mycobacterium tuberculosis isolates resistant to rifampicin. Use for large numbers of tubercular strains and susceptibility to streptomycin; Virus which infects and multiplies within live mycobacteria; Technology of rapid phage-based...

  • Evaluation of microscopic observation drug susceptibility assay for diagnosis of multidrugresistant Tuberculosis in Viet Nam.  // BMC Infectious Diseases;2012, Vol. 12 Issue 1, p49 

    The article presents information on a study which analyzes the use of microscopic observation drug susceptibility (MODS) assay as a direct rapid drug susceptibility testing (DST) method for multidrugresistant Tuberculosis (MDR-TB) screening in sputum samples. The study included all adult TB...

  • Incidence of Multidrug-Resistant Tuberculosis in Urban and Rural India and Implications for Prevention. Almeida, Deepak; Rodrigues, Camilla; Lalwani, Ajit; Mehta, Ajita; Gothi, G.D.; Mehta, Pravin // Clinical Infectious Diseases;6/15/2003, Vol. 36 Issue 12, pe152 

    We compared the incidence of multidrug resistance in 150 consecutive Mycobacterium tuberculosis isolates obtained from a rural center (in Sakawar, India) and an urban tertiary care center (in Mumbai, India). The study highlights an alarmingly high percentage of multidrug-resistant M....

  • Molecular diagnostics in tuberculosis. Cheng, V. C. C.; Yew, W. W.; Yuen, K. Y. // European Journal of Clinical Microbiology & Infectious Diseases;Nov2005, Vol. 24 Issue 11, p711 

    Molecular diagnostics in tuberculosis has enabled rapid detection of Mycobacterium tuberculosis complex in clinical specimens, identification of mycobacterial species, detection of drug resistance, and typing for epidemiological investigation. In the laboratory diagnosis of tuberculosis, the...

  • Drug Resistance in Pulmonary Tuberculosis in Istanbul. Kilicaslan, Z.; Albal, H.; Kiyan, E.; Aydemir, N.; Seber, E. // European Journal of Clinical Microbiology & Infectious Diseases;Oct2002, Vol. 21 Issue 10, p763 

    The article cites a study that was conducted to determine the rate of drug resistance in patients with pulmonary tuberculosis in Istanbul, Turkey, during 1999. It states that anti-tuberculosis drug resistance, especially multi-drug resistance, is a major factor threatening the success of...

  • Molecular Diversity of Drug Resistant Mycobacterium Tuberculosis Strains in Western Turkey. Sürücüoğlu, Süheyla; Günal, Selami; Özkütük, Nuri; Biçmen, Can; Özsöz, Ayşe; Gazi, Hörü; Durmaz, Rıza // Balkan Medical Journal;Jun2012, Vol. 29 Issue 2, p160 

    Objective: The aim of this study was to investigate the molecular diversity and clonal relationship of drug resistant Mycobacterium tuberculosis strains isolated in Western Turkey. Materials and Methods: A total of 87 strains isolated between 2006 and 2009, eight of which were rifampicin...

  • HIV prevalence and testing practices among tuberculosis cases in London: a missed opportunity for HIV diagnosis? A J Rodger // Thorax;Jan2010, Vol. 65 Issue 1, p63 

    BACKGROUND: Universal testing for HIV in patients with tuberculosis (TB) has been advocated for over a decade. The aim of this study was to describe the prevalence and testing practices of HIV in TB centres in London. METHODS: A cohort study was undertaken of all patients with TB in Greater...

  • Fluoroquinolone resistance in Mycobacterium tuberculosis isolates: associated genetic mutations and relationship to antimicrobial exposure. Jann-Yuan Wang; Li-Na Lee; Hsin-Chih Lai; Shu-Kuan Wang; I-Shiow Jan; Chong-Jen Yu; Po-Ren Hsueh; Pan-Chyr Yang // Journal of Antimicrobial Chemotherapy (JAC);May2007, Vol. 59 Issue 5, p860 

    Objectives We assessed the fluoroquinolone (FQ) susceptibility of clinical isolates of Mycobacterium tuberculosis in an endemic area. The genetic mutations responsible for FQ resistance were also evaluated. Methods A total of 420 M....

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics