COMMENTARY: Sitagliptin improved glycemic control and β-cell function in type 2 diabetes

Pugh, Jacqueline A.
March 2007
ACP Journal Club;Mar/Apr2007, Vol. 146 Issue 2, p39
Academic Journal
The article presents the author's views about a study which states that sitagliptin improved glycemic control and ß-cell function in type 2 diabetes. Sitagliptin is a member of the dipeptidyl peptidase-4 inhibitor class of oral agents that block the degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic peptide. Both of these are released in response to food intake, and both in turn stimulate insulin and suppress glucagon release.


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