Needles galore, but no place to sew

April 2007
Nature Medicine;Apr2007, Vol. 13 Issue 4, p387
Academic Journal
The article comments that the results of large-scale genetic sequencing projects to identify mutations related to cancer and psychiatric disorders will be limited, unless good animal models are developed to test their contribution to disease. Signal-to-noise ratio is important during the throughput screening of a chemical library. It is also a cause of concern including the lack of models to test the relevance of candidate genes.


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