Testosterone Replacement Therapy: What We Know Is Not Yet Enough

Isidori, Andrea M.; Lenzi, Andrea
January 2007
Mayo Clinic Proceedings;Jan2007, Vol. 82 Issue 1, p11
Academic Journal
The author reflects on the factors to be considered in using testosterone replacement therapy to address a wide range of problems in aging men. According to the author, important scientific questions need to be answered with solid data from well-designed observational studies before an optimal trial can be designed. He said that it is crucial to identify the targets of androgen treatment that are relevant enough to justify the risks and costs of a larger randomized clinical trials.


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