Malaria Vaccines Based on the Plasm odium falciparum Merozoite Surface Protein 3--Should We Avoid Amino Acid Sequence Polymorphisms or Embrace Them?

Saul, Allan
January 2007
Journal of Infectious Diseases;1/15/2007, Vol. 195 Issue 2, p171
Academic Journal
The article offers information on the strategies to develop a malaria vaccine with the correct chemical combination for achieving immunity against malaria. It is suggested that correct immune selection is crucial in developing a highly effective multi-component malaria vaccine. Prototype vaccines with blood-stage antigens like merozoite surface protein 3 which used antibody-dependent cellular inhibition mechanism against the infection were found quite effective.


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