TITLE

Lock and key approach to "hidden" encephalitis

AUTHOR(S)
Thompson, E. J.
PUB. DATE
August 2006
SOURCE
Journal of Neurology, Neurosurgery & Psychiatry;Aug2006, Vol. 77 Issue 8, p901
SOURCE TYPE
Academic Journal
DOC. TYPE
Editorial
ABSTRACT
The author reflects on the study on the use of polymerase chain reaction and immunoglobulin G in treating encephalitis. He emphasizes the importance of providing support to neurologists by giving them access to laboratories where they could conduct their experiment for further improvements for the diagnosis and treatment of the disease. A brief overview on the details of the study conducted by C.J.M. Sindic and colleagues is presented.
ACCESSION #
21992712

 

Related Articles

  • Comparison of reverse transcription loop-mediated isothermal amplification, conventional PCR and real-time PCR assays for Japanese encephalitis virus. Zhiyong Chen; Yuxue Liao; Xuemei Ke; Jie Zhou; Yixiong Chen; LuLu Gao; Qing Chen; Shouyi Yu // Molecular Biology Reports;Aug2011, Vol. 38 Issue 6, p4063 

    We developed and evaluated a reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for detecting Japanese encephalitis virus (JEV). The sensitivity of the JEV RT-LAMP assay was in concordance with that of real-time RT-PCR and 10-fold more sensitive than that of...

  • Prognostic value of intrathecal antibody production and DNA viral load in cerebrospinal fluid of patients with herpes simplex encephalitis. Hjalmarsson, Anders; Granath, Fredrik; Forsgren, Marianne; Brytting, Maria; Blomqvist, Paul; Sk├Âldenberg, Birgit // Journal of Neurology;Aug2009, Vol. 256 Issue 8, p1243 

    Herpes simplex encephalitis is a devastating disease. In the early 1980s our group conducted a nationwide clinical trial of acyclovir versus vidarabine in patients with herpes simplex encephalitis in whom intrathecal herpes simplex virus (HSV) antibodies were assayed. The purpose of this study...

  • Ebola viral load at diagnosis associates with patient outcome and outbreak evolution. de La Vega, Marc-Antoine; Caleo, Grazia; Audet, Jonathan; Xiangguo Qiu; Kozak, Robert A.; Brooks, James I.; Kern, Steven; Wolz, Anja; Sprecher, Armand; Greig, Jane; Lokuge, Kamalini; Kargbo, David K.; Kargbo, Brima; Di Caro, Antonino; Grolla, Allen; Kobasa, Darwyn; Strong, James E.; Ippolito, Giuseppe; Van Herp, Michel; Kobinger, Gary P. // Journal of Clinical Investigation;12/1/2015, Vol. 125 Issue 12, p4421 

    Background: Ebola virus (EBOV) causes periodic outbreaks of life-threatening EBOV disease in Africa. Historically, these outbreaks have been relatively small and geographically contained; however, the magnitude of the EBOV outbreak that began in 2014 in West Africa has been...

  • Diagnosis of Barmah Forest Virus Infection by a Nested Real-Time SYBR Green RT-PCR Assay. Hueston, Linda; Toi, Cheryl S.; Jeoffreys, Neisha; Sorrell, Tania; Gilbert, Gwendolyn // PLoS ONE;Jul2013, Vol. 8 Issue 7, p1 

    Barmah Forest virus (BFV) is a mosquito borne (+) ssRNA alphavirus found only in Australia. It causes rash, myalgia and arthralgia in humans and is usually diagnosed serologically. We developed a real-time PCR assay to detect BFV in an effort to improve diagnosis early in the course of...

  • Laboratory Diagnosis and Characteristics of Breakthrough Varicella in Children. Weinmann, Sheila; Chun, Colleen; Mullooly, John P.; Riedlinger, Karen; Houston, Heather; Loparev, Vladimir N.; Schmid, D. Scott; Seward, Jane F. // Journal of Infectious Diseases;Mar2008 Supplement 2, Vol. 197, pS132 

    The atypical features of varicella in vaccinated persons (breakthrough varicella [BTV]) present diagnostic challenges. We examined varicella-zoster virus (VZV) polyinerase chain reaction (PCR) and immunoglobulin (Ig) M and IgG serologic test results for confirming BTV cases. Among 33 vaccinated...

  • Polymerase Chain Reaction for Diagnosing Invasive Aspergillosis: Getting Closer but Still a Ways to Go. Donnelly, J. Peter // Clinical Infectious Diseases;2/15/2006, Vol. 42 Issue 4, p487 

    The article presents the author's comment on the paper "The Evolution and Evaluation of a Whole Blood Polymerase Chain Reaction Assay for the Detection of Invasive Aspergillosis in Hematology Patients in a Routine Clinical Setting," that appear in the February 15, 2006 issue of the journal...

  • Laboratory Diagnosis and Therapy of Invasive Fungal Infections. Willinger, B. // Current Drug Targets;Apr2006, Vol. 7 Issue 4, p513 

    Diagnosing fungal infections remains a problem, particularly in the immunocompromised patient. Symptoms are mostly non-specific and colonization is difficult to distinguish from invasive disease. Existing diagnostic tools often lack sensitivity. Thus, the combination of various diagnostic tools...

  • Herpes Zoster and Postherpetic Neuralgia: Prevention and Management. FASHNER, JULIA; BELL, AMANDA L. // American Family Physician;6/15/2011, Vol. 83 Issue 12, p1432 

    Herpes zoster (shingles) is diagnosed clinically by recognition of the distinctive, painful vesicular rash appearing in a unilateral, dermatomal distribution. An estimated 1 million cases occur in the United States each year, and increasing age is the primary risk factor. Laboratory testing,...

  • Molecular response in acute promyelocytic leukemia: a direct comparison of regular and real-time RT-PCR. Liu, Y.-F.; Zhu, Y.-M.; Shen, S.-H.; Shen, Z.-X.; Li, J.-M.; Chen, S.-J.; Chen, Z.; Jiong, H. U. // Leukemia (08876924);Aug2006, Vol. 20 Issue 8, p1393 

    Evaluation of molecular response is important for the diagnosis and monitoring of minimal residual disease in patients with acute promyelocytic leukemia (APL). In this study, we analyzed the molecular response by regular reverse transcription-polymerase chain reaction (RT-PCR) and quantitative...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics