Stem Cell Research: Past, Present, and Future
- Into the Limelight. YANDELL, KATE // Scientist;Oct2015, Vol. 29 Issue 10, p66
The article talks about importance of glial cells including astrocytes, oligodendrocytes, and microglia in brain function and structure. It discusses glial cell's function to provide structural integrity to the brain and other functions which are being discovered by scientists. It also mentions...
- PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors. Schrenk-Siemens, Katrin; Wende, Hagen; Prato, Vincenzo; Song, Kun; Rostock, Charlotte; Loewer, Alexander; Utikal, Jochen; Lewin, Gary R; Lechner, Stefan G; Siemens, Jan // Nature Neuroscience;Jan2015, Vol. 18 Issue 1, p10
Human sensory neurons are inaccessible for functional examination, and thus little is known about the mechanisms mediating touch sensation in humans. Here we demonstrate that the mechanosensitivity of human embryonic stem (hES) cell-derived touch receptors depends on PIEZO2. To recapitulate...
- A Matter of Life. Silverman, Rogena Schuyler // Rehab Management: The Interdisciplinary Journal of Rehabilitatio;Dec2006, Vol. 19 Issue 10, p8
The article comments on issues related to stem cell research. The author mentions that legislators, religious leaders and scientists have debated over the moral implications of funding studies that usually use stem cells derived from human embryos and adult bone marrow. She also states that with...
- Neural lineage development of rhesus monkey embryonic stem cells: Insight of neurogenesis and gliogenesis in vitro. Hongwei Chen; Yu Mao; Bin Li; Qiang Wei; Jing Zhang; Jinhuan Wang; Jianhong Wang; Shufen Wang; Tao Tan; Xiuzhen Zhang; Jian Li; Yuanye Ma; Weizhi Ji // Cell Research;Aug2008 Supplement, Vol. 18, pS148
Neurons and glia are important targets of embryonic stem (ES) cell research, promising a renewable source of these differentiated cells for basic research and regenerative medicine. Though many subtypes of nerve cells have differentiated from ES cells in vitro, their lineal relations are not...
- Human iPS Cells: Science and Ethics. Crook, Jeremy Micah // Open Stem Cell Journal;2010 Special Issue, p1
An introduction to the journal is presented in which the editor discusses articles on the science and ethic of human induced pluripotent stem (iPS) cells, the human somatic cell reprogramming, and the biological equivalent of the iPS and embryonic stem (ES) cells.
- The Molecular Profiles of Neural Stem Cell Niche in the Adult Subventricular Zone. Cheol Lee; Jingqiong Hu; Ralls, Sherry; Toshio Kitamura; Y. Peng Loh; Yanqin Yang; Yohsuke Mukouyama; Sohyun Ahn // PLoS ONE;Nov2012, Vol. 7 Issue 11, Special section p1
Neural stem cells (NSCs) reside in a unique microenvironment called the neurogenic niche and generate functional new neurons. The neurogenic niche contains several distinct types of cells and interacts with the NSCs in the subventricular zone (SVZ) of the lateral ventricle. While several...
- Replacement Neurons. // Technology Review;May/Jun2010, Vol. 113 Issue 3, p96
The article presents a study which shows the ability of scientists to transform mouse skin cells into brain cells without returning them to their embryonic state.
- Huntington's and Brains and Stem Cells. Breindl, Anette // BioWorld Today;6/10/2013, Vol. 24 Issue 110, Special section p1
The article offers information on research that reveals a way to coax endogenous neural stem cells into producing medium spiny neurons.
- In vitro differentiation of cultured human CD34+ cells into astrocytes. Venkatesh, Katari; Srikanth, Lokanathan; Vengamma, Bhuma; Chandrasekhar, Chodimella; Sanjeevkumar, Akula; Mouleshwara Prasad, Bodapati Chandra; Krishna Sarma, Potukuchi Venkata Gurunadha // Neurology India;Jul/Aug2013, Vol. 61 Issue 4, p383
Background: Astrocytes are abundantly present as glial cells in the brain and play an important role in the regenerative processes. The possible role of stem cell derived astrocytes in the spinal cord injuries is possible related to their influence at the synaptic junctions. Aim: The present...