Low-molecular-weight heparins as adjunctive therapy to thrombolytics: extracting the best data

Bailey, Alison L.; Steinhubl, Steven R.
May 2006
CMAJ: Canadian Medical Association Journal;5/9/2006, Vol. 174 Issue 10, p1431
Academic Journal
Discusses a study that evaluated the safety and efficacy of the thrombolytic drug tenecteplase plus either enoxaparin or unfractionated heparin in cases of ST-segment elevation myocardial infarction by doing a pooled analysis of data from the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT)-3 and ASSENT-3 PLUS trials. Purpose of the ASSENT-3 trial; Reduction in rates of reinfarction and recurrent ischemia; Risk of intracranial hemorrhage among patients older than 75 years who received enoxaparin and tenecteplase.


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