What is the best evidence for determining harms of medical treatment?

Vandenbroucke, Jan P.
February 2006
CMAJ: Canadian Medical Association Journal;2/28/2006, Vol. 174 Issue 5, p645
Academic Journal
The article examines a study that compared evidence on adverse effects from medical interventions reported in randomized and nonrandomized studies. Data from observational studies on adverse effects must be considered aside from data from randomized controlled trials. Most of the adverse effects reported by the authors were said to be pharmacologically predictable.


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