Why does airway inflammation persist after the smoking stops?

Hogg, J. C.
February 2006
Thorax;Feb2006, Vol. 61 Issue 2, p96
Academic Journal
The paper clarifies the precise mechanisms for either the amplification step found in association with the group that develop chronic obstructive pulmonary disease (COPD) or the persistence of the inflammatory immune response following the removal of the smoking stimulus. Lapperre and colleagues found that as a group, the ex-smokers had higher numbers of CD4+ lymphocytes and plasma cells than current smokers. There was no difference in the numbers of neutrophils, macrophages, or CD8+ cells between the groups.


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