Pulmonary hypertension after splenectomy: a consequence of loss of the splenic filter or is there something more?

Peacock, A. J.
December 2005
Thorax;Dec2005, Vol. 60 Issue 12, p983
Academic Journal
The article discusses pulmonary hypertension after splenectomy. Chronic thromboembolic disease has been defined as "pulmonary hypertension caused by the absence of thrombus resolution after acute pulmonary embolism which has resulted in sustained obstruction of the pulmonary circulation." This view is probably outdated because in 50% of cases there is no definite history of venous thrombosis and it is likely that many cases are a consequence of in situ thrombosis. It is clear that splenectomy is a risk for thromboembolic hypertension, particularly in patients who have had splenectomy for a haemolytic disorder.


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