Oxygen: the good, the bad, and the necessary

Troosters, T.
December 2004
Thorax;Dec2004, Vol. 59 Issue 12, p1005
Academic Journal
The article focuses on the use of oxygen therapy in chronic obstructive pulmonary disease (COPD). Long term oxygen therapy (LTOT) is one of the few treatments which has significant survival benefits in patients with severe hypoxaemia. In less severe hypoxaemic patients the benefits of LTOT on survival are less clear. Other benefits of oxygen administration are generally accepted. Reduced ventilation, especially during exercise, helps to avoid dynamic hyperinflation and hence reduces symptoms and increases exercise tolerance in the majority of patients with COPD, even in patients with mild hypoxaemia.


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