TITLE

Review: Low-molecular-weight heparin reduces recurrent venous thromboembolism better than unfractionated heparin: COMMENTARY

AUTHOR(S)
Dunn, Andrew
PUB. DATE
May 2005
SOURCE
ACP Journal Club;May/Jun2005, Vol. 142 Issue 3, p71
SOURCE TYPE
Academic Journal
DOC. TYPE
Editorial
ABSTRACT
In this article the author reports that previous meta-analyses comparing fixed-dose low-molecular-weight heparin (LMWH) with adjusted-dose unfractionated heparin (UFH) for treatment of acute venous thromboembolism (VTE) showed that LMWH reduces all-cause mortality, and found trends for reduction of recurrent VTE and major bleeding. The meta-analysis used a comprehensive search strategy and included the most recent randomized controlled trials, thereby presenting an aggregate of the most current evidence. Limitations include the use of trials that compared LMWH with subcutaneous UFH, which may have contributed to the finding of superiority of LMWH.
ACCESSION #
17116537

 

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