Genetic association studies in Thorax

Hail, I. P.; Blakey, J. D.
May 2005
Thorax;May2005, Vol. 60 Issue 5, p357
Academic Journal
The article presents information on a guide to assessing the validity of genetic association studies in respiratory disease for publication in the journal "Thorax." Well designed studies have the potential to provide functionally relevant data on the pathophysiology of disease initiation and severity. The majority of the submitted genetic association studies use a case-control design. For any given genetic association study an initial power calculation should be undertaken to determine the power of the study to detect effects.


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