Thalidomide and cancer cachexia: old problem, new hope?

Stroud, M.
April 2005
Gut;Apr2005, Vol. 54 Issue 4, p447
Academic Journal
This article focuses on role of thalidomide in weight loss in patients with advanced pancreatic cancer. The cancer cachexia syndrome is common. Significant weight loss occurs in approximately 50% of oncology patients, with even higher values in those with gastrointestinal tumors. In pancreatic cancer, approximately 80% of patients will become severely malnourished. Greater comprehension of the mechanisms underlying cancer cachexia has come from examination of the systems that regulate cellular metabolism.


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