Pancreaticobiliary biofilm: is cholesterol the answer?

Kozarek, R. A.
March 2005
Gut;Mar2005, Vol. 54 Issue 3, p326
Academic Journal
The article presents information related to the pancreaticobiliary biofilm. Cholesterol stone formation may be a physiological response to limit bacterial biofilm development in bile, its incorporation into plastic polymers may be a novel way to prevent biofilm development and subsequent stent occlusion in patients with biliary prostheses. Bacteria in the biliary tree have been the bane of surgeons and gastroenterologists alike. On the one hand, up to 50% of patients with chronic cholecystitis have positive bile cultures, as do 75% of patients with acute cholecystitis, and virtually 100% of individuals with cholangitis.


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