Skeletal muscle weakness, fatigue and sarcoidosis

Costabela, U.
January 2005
Thorax;Jan2005, Vol. 60 Issue 1, p1
Academic Journal
This article reports that sarcoidosis is a multisystem granulomatous disorder that may involve many organs. Beside organ specific symptoms, non-specific constitutional complaints such as fatigue and general weakness are frequent. Fatigue and general weakness may be the reason why patients with sarcoidosis frequently experience exercise intolerance. Other factors may therefore be involved in the development of skeletal muscle weakness. One could be reduced physical activity which can induce general deconditioning in these patients who complain of fatigue, general malaise and depression, all of which will probably reduce the patients' physical activities. The levels of muscle enzymes such as creatine phosphokinase may be raised.


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