Preeclampsia: Theories and speculations

Livingston, Jeffrey C.; Maxwell, Bryan D.
March 2003
Wiener Klinische Wochenschrift;2003, Vol. 115 Issue 5/6, p145
Academic Journal
This article focuses on theories and speculation of Preeclampsia. Preeclampsia is a disease unique to human pregnancy characterized by hypertension and proteinuria. The clinical manifestations of preeclampsia range from mild hypertension at term to severe hypertensive crisis, seizures, and development of HELLP syndrome. The exact etiology of preeclampsia remains elusive. The physiologic endpoint in women with preeclampsia is endothelial cell damage. Hypertension in preeclampsia is due to vasoconstriction. Women with chronic hypertension have up to a 25% risk of developing superimposed preeclampsia.


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