Colorectal cancer: does early detection matter?

Rozen, P.
May 2001
Postgraduate Medical Journal;May2001, Vol. 77 Issue 907, p289
Academic Journal
The survival from colorectal cancer is related directly to the degree of malignant invasion through the bowel wall that has occurred by the time of diagnosis and treatment. Only about 50% of all patients, symptomatic at the time of their diagnosis, will be alive five years after treatment. In contrast, all three large scale population randomised trials of faecal occult blood screening, in Great Britain, the U.S. and Scandinavia, have demonstrated a significant reduction of 15%-30% in mortality caused by colorectal cancer. This increased survival was due to detecting more asymptomatic persons with early stage, less invasive, and therefore a surgically curable disease.


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