Endoscopic ultrasound: a useful tool to assess the mediastinum in patients with lung cancer?

Penman, I.; Fergusson, R. J.
February 2002
Thorax;Feb2002, Vol. 57 Issue 2, p95
Academic Journal
Mediastinal involvement either by direct invasion or by spread to lymph nodes is seen at diagnosis in up to 50% of patients with non-small cell lung cancer and has a significant impact on both treatment and prognosis. Ipsilateral or subcarinal lymph node involvement is associated with a 5 year survival of 7-13% and usually precludes resection, but may identify a subset of patients who might benefit from neoadjuvant therapy. Contralateral nodal disease is surgically incurable with fewer than 5% of patients surviving 5 years. Accurate assessment of the mediastinum at the time of diagnosis is therefore vital for patients deemed suitable for potentially curative treatment.


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