- CORRIGENDUM: Cytochrome P450 3A5 Genotype Is Associated With Verapamil Response in Healthy Subjects. // Clinical Pharmacology & Therapeutics;Jul2010, Vol. 88 Issue 1, p138
A correction to the article "Cytochrome P450 3A5 Genotype Is Associated With Verapamil Response in Healthy Subjects," that was published in the previous issue is presented.
- Correction: Goldbeck, R.A., et ah Early Events, Kinetic Intermediates and the Mechanism of Protein Folding in Cytochrome c. Int. J. Mol Sci. 2009,10,1476-1499. // International Journal of Molecular Sciences;Apr2009, Vol. 10 Issue 4, p1728
A correction to the article about the kinetic intermediates and the mechanism of the protein folding in cytochrome that was published in the previous issue is presented.
- Cytochrome P450 Retinoic Acid 4-Hydroxylase Inhibitors: Potential Agents for Cancer Therapy. Njar, V.C.O. // Mini Reviews in Medicinal Chemistry;Jun2002, Vol. 2 Issue 3, p261
Retinoids play a crucial role in cellular differentiation and proliferation of epithelial tissue and their utility in oncology and dermatology is well documented. This mini review focuses on the role of all-trans-retinoic acid (ATRA or RA), the principal endogenous retinoid and its metabolism in...
- Design and applicability of DNA arrays and DNA barcodes in biodiversity monitoring. Hajibabaei, Mehrdad; Singer, Gregory A. C.; Clare, Elizabeth L.; Hebert, Paul D. N. // BMC Biology;2007, Vol. 5, p24
Background: The rapid and accurate identification of species is a critical component of large-scale biodiversity monitoring programs. DNA arrays (micro and macro) and DNA barcodes are two molecular approaches that have recently garnered much attention. Here, we compare these two platforms for...
- The Cytochrome P450 Superfamily: Biochemistry, Evolution and Drug Metabolism in Humans. P. B. Danielson // Current Drug Metabolism;Dec2002, Vol. 3 Issue 6, p561
Cytochrome P450s comprise a superfamily of heme-thiolate proteins named for the spectral absorbance peak of their carbon-monoxide-bound species at 450 nm. Having been found in every class of organism, including Archaea, the P450 superfamily is believed to have originated from an ancestral gene...
- Important Liver Molecule Discovered. // Nutrition Health Review: The Consumer's Medical Journal;2002, Issue 83, p7
Reports on the discovery of the liver molecule PXR responsible for metabolizing majority of drugs taken by humans by chemists at the University of North Carolina in Chapel Hill, North Carolina. Regulator of a protein called cytochrome P450-3A; Effect of interactions involving the regulator...
- Modulation of rat liver cytochrome P450 by protein restriction assessed by biochemical and bacterial mutagenicity methods. Cancino-Badías, L.; Reyes, R. E.; Nosti, R.; Pérez, I.; Dorado, V.; Caballero, S.; Soria, A.; Camacho-Carranza, R.; Escobar, D.; Espinosa-Aguirre, J. J. // Mutagenesis;Mar2003, Vol. 18 Issue 2, p217-b
A correction to the article "Modulation of rat liver cytochrome P450 by protein restriction assessed by biochemical and bacterial mutagenicity methods," that was published in the 18 issue is presented.
- Simvastatin + CYP3A4 inhibitors: serious/fatal rhabdomyolysis cases. // Reactions Weekly;Jan2015, Vol. 1533 Issue 1, p7
The article focuses on the report released by the Centre for Adverse Reactions Monitoring (CARM) regarding life-threatening and fatal cases of rhabdomyolysis specifically on potent cytochrome P450 3A4 (CYP3A4) inhibitors.
- Genotyping of CYP Enzymes. Myers, Rene // Drug Discovery & Development;Jul/Aug2002, Vol. 5 Issue 7, p102
Focuses on the use of pyrosequencing technology in genotyping cytochrome P450 (CYP) enzymes. Reliability of the technology; Provisions of pyrosequencing analysis; Role of CYP in the metabolism of drugs. INSET: CYP2D6 Alleles.