- Bacteriophage-Loaded Nanostructured Lipid Carrier: Improved Pharmacokinetics Mediates Effective Resolution of Klebsiella pneumoniae-Induced Lobar Pneumonia. Singla, Saloni; Harjai, Kusum; Katare, Om Prakash; Chhibber, Sanjay // Journal of Infectious Diseases;7/15/2015, Vol. 212 Issue 2, p325
This study examined the therapeutic and prophylactic potential of bacteriophages in a mouse model of Klebsiella pneumoniae lobar pneumonia. Phages were administered intraperitoneally. Liposome-entrapped phages (LP) were effective in treating infection, even when therapy was delayed by 3 days...
- Role of the Single-Stranded DNA-Binding Protein SsbB in Pneumococcal Transformation: Maintenance of a Reservoir for Genetic Plasticity. Attaiech, Laetitia; Olivier, Audrey; Mortier-Barriére, Isabelle; Soulet, Anne-Lise; Granadel, Chantal; Martin, Bernard; Polard, Patrice; Claverys, Jean-Pierre // PLoS Genetics;Jun2011, Vol. 7 Issue 6, Special section p1
Bacteria encode a single-stranded DNA (ssDNA) binding protein (SSB) crucial for genome maintenance. In Bacillus subtilis and Streptococcus pneumoniae, an alternative SSB, SsbB, is expressed uniquely during competence for genetic transformation, but its precise role has been disappointingly...
- Literature Reviews: Clinical Outcomes of Bacteremic Pneumococcal Pneumonia in the Era of Antibiotic Resistance. Farjo, Rand S.; Gilsdorf, Janet R. // Clinical Pediatrics;Sep2002, Vol. 41 Issue 7, p544
Reviews the book 'Clinical Outcomes of Bacteremic Pneumococcal Pneumonia in the Era of Antibiotic Resistance,' by J. Moroney, A. Fiore, and L. Harrison.
- Understanding S. Pneumoniae. Corry, Margarita; Whelan, Jacqueline // World of Irish Nursing & Midwifery;Sep2006, Vol. 14 Issue 8, p55
The article discusses the nature of streptococcus pneumonia also known as the pneumococcal pneumonia, a potentially vaccine-preventable disease which is among the leading causes of illness and death in young children worldwide. The disease is caused by an anaerobic gram positive bacterium. It is...