TITLE

Case of recurrence of spiradenoma in palpebral conjunctiva

AUTHOR(S)
Oie, Shinya; Sawada, Akira; Mochizuki, Kiyofumi; Tsuji, Kozue; Hirose, Yoshinobu; Saigo, Chiemi; Yoshikawa, Hiroshi
PUB. DATE
July 2014
SOURCE
BMC Ophthalmology;2014, Vol. 14 Issue 1, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
Background To report a rare case of a recurrence of spiradenoma that developed in the upper eyelid. Case presentation A 49-year-old woman who had a second recurrence of a tumor in the right palpebral conjunctiva underwent local resection of the lesion with adjunctive cryotherapy to the surgical site. The tumor consisted of smooth, round to oval nodular lesions approximately 1- 3 mm in size with enlarged blood vessels. Histopathologically, the solid and wellcircumscribed nodule was located beneath the conjunctival epithelium. It was composed of cells with slightly basophilic-to-clear cytoplasm and round-to-oval nuclei arranged in a trabecular pattern. Periodic acid-Schiff stain was positive in the cytoplasm, and the staining disappeared after digesting by diastase. Many cells in mitosis were observed throughout the tumor but no necrotic cells. Immunohistochemistry showed that the Ki-67 labeling index was 12%. From these findings, we diagnosed this tumor as a recurrence of the spiradenoma. There has been no recurrence and no signs of malignancy in the 6 months after the surgical excision. Conclusion Our findings indicate that a spiradenoma should be completely excised surgically because of malignant transformation after repeated recurrences.
ACCESSION #
97085302

 

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