Elevated Lipoprotein(a) in a Newborn With Thrombosis and a Family History of Dyslipidemia

Bravo-valenzuela, Nathalie Jeanne Magioli
December 2013
Pediatric Cardiology;Dec2013, Vol. 34 Issue 8, p2056
Academic Journal
Case Study
This paper reports a rare case of elevated lipoproteinemia(a) that evolved into thrombosis during the neonatal period. During the first days of life, the patient presented with an intracardiac thrombus, pulmonary thromboembolism and a hemorrhagic stroke. Initially, the results of the blood tests performed to screen for thrombophilic diseases were normal for the patient’s age. The maternal dyslipidemia and the family’s positive history of thromboembolism drew attention to an underlying, inherited, thrombophilic defect. Upon further investigation of the thrombophilia, the increase in lipoprotein(a) levels found in the mother and infant enabled the diagnosis of hyperlipoprotein(a) and the administration of appropriate therapy.


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