Primitive Myxoid Mesenchymal Tumor of Infancy: A Report of a Further Case with Locally Aggressive Behavior

January 2011
Pediatric & Developmental Pathology;Jan/Feb2011, Vol. 14 Issue 1, p75
Academic Journal
Case Study
We report a case of an 8-month-old child with a primitive myxoid mesenchymal tumor of infancy arising in the thenar eminence. The lesion recurred after conservative excision and was ultimately nonresponsive to chemotherapy, necessitating partial amputation. The patient remains free of disease 5 years after this radical surgery. This is the 1st report of such a tumor since it was initially described by Alaggio and colleagues in 2006. The pathologic differential diagnosis is discussed.


Related Articles

  • Chordoma Characterization of Significant Changes of the DNA Methylation Pattern. Rinner, Beate; Weinhaeusel, Andreas; Lohberger, Birgit; Froehlich, Elke Verena; Pulverer, Walter; Fischer, Carina; Meditz, Katharina; Scheipl, Susanne; Trajanoski, Slave; Guelly, Christian; Leithner, Andreas; Liegl, Bernadette // PLoS ONE;Mar2013, Vol. 8 Issue 3, p1 

    Chordomas are rare mesenchymal tumors occurring exclusively in the midline from clivus to sacrum. Early tumor detection is extremely important as these tumors are resistant to chemotherapy and irradiation. Despite continuous research efforts surgical excision remains the main treatment option....

  • Congenital sacrococcygeal PNET and chemotherapy. Hawkes, Colin Patrick; Betts, David R.; O'Brien, John; O'Sullivan, Maureen J.; Capra, Michael // Indian Journal of Medical & Paediatric Oncology;Jul-Sep2012, Vol. 33 Issue 3, p182 

    We present the case of a congenital localised sacrococcygeal primitive neuroectodermal tumor treated aggressively with surgical resection and modified age-appropriate adjuvant chemotherapy. The conventional combination chemotherapy of vincristine, adriamycin, cyclophosphamide, ifosfamide and...

  • Successful treatment of infants with localized neuroblastoma based on their MYCN status. Iehara, Tomoko; Hamazaki, Minoru; Tajiri, Tatsuro; Kawano, Yoshifumi; Kaneko, Michio; Ikeda, Hitoshi; Hosoi, Hajime; Sugimoto, Tohru; Sawada, Tadashi // International Journal of Clinical Oncology;Jun2013, Vol. 18 Issue 3, p389 

    Background: The aim of this study was to evaluate the effectiveness of post-surgical chemotherapy for infants with localized neuroblastoma without MYCN amplification (MNA), and determine whether risk classification using MNA is reasonable. Methods: Four hundred and fourteen eligible patients...

  • Margin status and multimodal therapy in infantile fibrosarcoma. Sulkowski, Jason; Raval, Mehul; Browne, Marybeth // Pediatric Surgery International;Aug2013, Vol. 29 Issue 8, p771 

    Purpose: The rarity of infantile fibrosarcoma (IF) has precluded comprehensive treatment evaluation. The purpose of this study was to better define the extent of surgical resection required and the role of chemotherapy. Methods: Patients (0-2 years) with IF were evaluated from the National...

  • Intraoperative Chemotherapie nach radikaler Pleurektomie oder extrapleuraler Pneumonektomie. Ried, M.; Hofmann, H.-S. // Der Chirurg;Jun2013, Vol. 84 Issue 6, p492 

    Trimodality treatment including induction and/or adjuvant chemotherapy, surgical resection and in some cases radiotherapy offers a curative intention in selected patients with pleural malignancies (malignant pleural mesothelioma, thymoma with pleural spread). Nevertheless, locoregional tumor...

  • Primary osteosarcoma of the heart with long-term survival: A case report of laparoscopic resection of a metastatic sarcoma in the intestine. SHIKI FUJINO; NORIKATSU MIYOSHI; MASAYUKI OHUE; SHINGO NOURA; SHUICHI HAMAMOTO; KAZUYA OSHIMA; NOBUHITO ARAKI; YASUHIKO TOMITA; MASAHIKO YANO // Oncology Letters;2014, Vol. 8 Issue 4, p1599 

    Primary cardiac tumors are uncommon and cardiac osteosarcoma is a rare disease. While complete surgical resection is considered to be the best treatment option for cardiac osteosarcomas, local and metastatic recurrences present challenges and indicate a poor prognosis. A combination of surgical...

  • Clinical outcomes of pancreatic ductal adenocarcinoma resection following neoadjuvant chemoradiation therapy vs. chemotherapy. Satoi, Sohei; Yanagimoto, Hiroaki; Yamamoto, Tomohisa; Ohe, Chisato; Miyasaka, Chika; Uemura, Yoshiko; Hirooka, Satoshi; Yamaki, So; Ryota, Hironori; Michiura, Taku; Inoue, Kentaro; Matsui, Yoichi; Tanigawa, Noboru; Kon, Masanori // Surgery Today;Jan2017, Vol. 47 Issue 1, p84 

    Purpose: We compared the clinical outcomes of pancreatic ductal adenocarcinoma (PDAC) resection after neoadjuvant chemoradiation therapy (NACRT) vs. chemotherapy (NAC). Methods: The study population comprised 81 patients with UICC stage T3/4 PDAC, treated initially by NACRT with S-1 in 40 and by...

  • Analysis of surgically excised breast masses in 119 pediatric patients. Knell, Jamie; Koning, Jeffery; Grabowski, Julia; Koning, Jeffery L; Grabowski, Julia E // Pediatric Surgery International;Jan2016, Vol. 32 Issue 1, p93 

    Purpose: Breast masses in children and adolescents are uncommon and the vast majority are benign. There are currently limited analyses of breast masses in this population and clinical management is highly variable between institutions and providers. The purpose of our study is to...

  • Condrosarcoma mesenquimal extraesquelético en región escapular. A propósito de un caso y revisión de la literatura. González, Rogelio González; Molina, Ronell Bologna; Gutiérrez, J. Rodrigo Muñoz; Tiscareño, Arcelia Mora // Revista Española de Patología;oct-dic2009, Vol. 42 Issue 4, p296 

    A 27 year old woman developed a painful swelling in the left scapular region accompanied by a limitation in movement following trauma. She underwent partial resection of the mass which was diagnosed histologically as an extraskeletal mesenchymal chondrosarcoma. She was treated with 5 cycles of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics