Streptococcal Toxic Shock Syndrome: Two Case Reports

Cander, Başar; Çalık, Göknil; Gül, Mehmet; Ertekin, Birsen; Girişgin, Sadık
March 2013
Journal of Academic Emergency Medicine / Akademik Acil Tip Olgu ;2013, Vol. 12 Issue 1, p49
Academic Journal
Case Study
Streptococcal toxic shock syndrome (STSS), the most common complication of skin infection is caused by a streptoccus. This syndrome is characterized by fever, hypotension and multiple organ failure. A 64 year old male patient with sudden onset of facial swelling and redness in the eye was admitted to hospital with these complaints. The patient had bilateral periorbital edema, purulent discharge from the right eye and swelling starting from the frontal region and spreading to the right side of the neck. The gram stain of the discharge was made and gram-positive cocci were seen in the abundant leukocytes. Antibiotics, corticosteroids, respiratory and hemodynamic support were given as the treatment protocol. A 70 year old male patient with sudden swelling in the eyes and discharge from the eyes was admitted with these complaints. Bilateral lid swelling, edema, hyperemia and temperature increase were present in the patient's physical examination. The gram stain of the discharge was made and gram-positive cocci and abundant leukocytes were seen. Antibiotic treatment was given. Toxic shock syndrome caused by streptococcus is a serious clinical condition rarely encountered in emergency department. Aggressive soft tissue infections in the clinical presentation, shock, ARDS and renal failure are generally associated with bacteremia. Despite aggressive treatment, the mortality rate is 80%.


Related Articles

  • Reply to Arends and Harkisoen. Linnér, Anna; Sjölin, Jan; Darenberg, Jessica; Henriques-Normark, Birgitta; Norrby-Teglund, Anna // Clinical Infectious Diseases;Jan2015, Vol. 60 Issue 2, p324 

    A response from the authors of the article "Clinical efficacy of polyspecific intravenous immunoglobulin therapy in patients with streptococcal toxic shock syndrome: a comparative observational study," published in a 2014 issue, is presented.

  • Intravenous Immunoglobulin Therapy for Streptococcal Toxic Shock Syndrome--A Comparative Observational Study. Kaul, Rupert; McGeer, Allison; Norrby-Teglund, Anna; Kotb, Malak; Schwartz, Benjamin; O'Rourke, Keith; Talbot, James; Low, Donald E. // Clinical Infectious Diseases;4/1/1999, Vol. 28 Issue 4, p800 

    Presents the results of a comparative observational study which investigated the effect of an intravenous immunoglobulin therapy for streptococcal toxic shock syndrome. Methodology; Results; Discussion.

  • Toxic Shock Syndrome: Management and Long-Term Sequelae. Chesney, P. Joan; Crass, Barbara A.; Polyak, Marcia B.; Wand, Philip J.; Warner, Thomas F.; Vergeront, James M.; Davis, Jeffrey P.; Tofte, Robert W.; Chesney, Russel W.; Bergdoll, Merlin S. // Annals of Internal Medicine;Jun82 Part 2, Vol. 96 Issue 6, p847 

    Deals with a study which determined treatments for and the sequelae of toxic shock syndrome. Methods; Results; Discussion.

  • Understanding toxic shock syndrome. Burnham, Jason; Kollef, Marin // Intensive Care Medicine;Sep2015, Vol. 41 Issue 9, p1707 

    The article offers information on toxic shock syndrome (TSS). Topics covered include the clinical presentation and diagnosis of staphylococcal toxic shock syndrome (SaTSS) and streptococcal toxic shock syndrome (SeTSS). Also mentioned is the importance of aggressive source controls including...

  • Comment on "Intravitreal Ampicillin Sodium for Antibiotic-Resistant Endophthalmitis: Streptococcus uberis First Human Intraocular Infection Report". Luigi Toma; Di Domenico, Enea Gino; Prignano, Grazia; Ensoli, Fabrizio // Journal of Ophthalmology;2014, p1 

    No abstract available.

  • Postpartum Thyrotoxicosis with Acute Suppurative Thyroiditis Caused by Peptostreptococcus. Nasıroğlu Imga, Narin; Tütüncü, Yasemin; Tuna, Mazhar Müslüm; Berker, Dilek; Güler, Serdar // Turkish Journal of Endocrinology & Metabolism;6/1/2015, Vol. 19 Issue 2, p67 

    Acute suppurative thyroiditis (ST) is caused by infection of the thyroid gland. Abscess formation in acute ST is a rare, but potentially life-threatening condition. Most patients with acute ST have predisposing conditions. Herein, we report a 24-year-old female who presented on the fifth...

  • Intravenous Immunoglobulin G Therapy in Streptococcal Toxic Shock Syndrome: A European Randomized, Double-Blind, Placebo-Controlled Trial. Darenberg, Jessica; Ihendyane, Nahla; Sjölin, Jan; Aufwerber, Ewa; Haidl, Sven; Follin, Per; Andersson, Jan; Norrby-Teglund, Anna // Clinical Infectious Diseases;8/1/2003, Vol. 37 Issue 3, p333 

    Evaluates the efficacy and safety of high-dose intravenous polyspecific immunoglobulin G (IVIG) as adjunctive therapy in streptococcal toxic shock syndrome (STSS). Mortality rate; Decrease in the sepsis-related organ failure assessment score in the IVIG group; Increase in plasma neutralizing...

  • Dilemmas in the Treatment of Invasive Streptococcus pyogenes Infections. Stevens, Dennis L. // Clinical Infectious Diseases;8/1/2003, Vol. 37 Issue 3, p341 

    Introduces a study by J. Darenberg et al in the August 1, 2003 issue of the journal 'Clinical Infectious Diseases,' about the use of human polyspecific immunoglobulin G (IgG) as adjunctive therapy for streptococcal toxic shock syndrome (Strep TSS). Biological potency of the treatment;...

  • Invasive Group A Streptococcal Disease. Steer, Andrew C.; Lamagni, Theresa; Curtis, Nigel; Carapetis, Jonathan R. // Drugs;2012, Vol. 72 Issue 9, p1213 

    Invasive group A streptococcal infections are uncommon, although serious, infections with high case fatality rates. Periodic resurgences in invasive group A streptococcal infections in industrialized countries have been reported from the 1980s onwards, with current estimates of incidence in...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics