TITLE

Treatment of Visual Hallucinations in Schizophrenia by Acetylcholinesterase Inhibitors: a case report

AUTHOR(S)
Abad, Nazir Hashemi; Doulatabad, Najafi Shala; Mohammadi, Ali; Ghafarian Srazi, Hamid Reza
PUB. DATE
December 2011
SOURCE
Iranian Journal of Psychiatry;Winter2011, Vol. 6 Issue 4, p161
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
Schizophrenia and various neurological disorders have some signs and symptoms. Visual hallucinations are one of such disorders. The related studies in some diseases for example Parkinson Disease and Lewy Body Dementia indicate that Acetylcholine (Ach) plays a significant role in neuropsychiatric manifestation and its association with visual hallucination; therefore, visual hallucinations occur due to the depletion of Ach. Drug therapies such as Cholinesterase inhibitors (ChEIs) for increasing Ach level may be beneficial in treating visual hallucination. AchEI's have been used in the treatment of visual hallucinations in Dementia and Parkinson's Disease. We thought that a similar Ach depletion may cause visual hallucinations in patients with schizophrenia and may provide a target for drug treatment. We had a patient with schizophrenia whose psychotic symptoms responded to the treatment plan, but her visual hallucination did not. However, the patient's visual hallucination successfully responded to Rivastigmine (AchEI). This case illustrates the use of an AchEI in the treatment of refractory visual hallucinations in a patient with schizophrenia.
ACCESSION #
78382065

 

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