Block and replace therapy using propylthiouracil and levothyroxine for Graves' disease during pregnancy

Gupta, Vishal
July 2012
Indian Journal of Endocrinology & Metabolism;Jul/Aug2012, Vol. 16 Issue 4, p660
Academic Journal
Case Study
The article describes the case of a 36-year-old married woman who received block and replace therapy using propylthiouracil and levothyroxine for the treatment of Graves' disease during pregnancy. The patient experienced symptoms such as grade 2 eye signs and proximal muscle weakness in all four limbs. She was recommended to receive methimazole.


Related Articles

  • Intermittent diplopia a diagnostic challenge. Digre, Kathleen B.; Charters, Lynda // Ophthalmology Times;7/1/2012, Vol. 37 Issue 13, p13 

    The article discusses the benign and serious causes of intermittent diplopia, which is very difficult eye disease to be diagnosed. It is given that benign can occur commonly as a result of dry eye and orbital-related problems, such as superior oblique myokymia and early Graves' disease. Serious...

  • Parálisis hipocalémica tirotóxica. Informe de un caso y revisión de la bibliografía. Castillo-Ramírez, Ayurabid; Velázquez-Figueroa, Juan Manuel; Rosales-Salyano, Víctor Hugo; Ochoa-Hein, Eric // Revista Medica del Hospital General de Mexico;abr-jun2011, Vol. 74 Issue 2, p87 

    Thyrotoxic hypokalemic periodic paralysis is an acute neuromuscular disorder characterized by reversible muscle weakness associated with thyrotoxicosis. It is considered an uncommon complication of thyrotoxicosis, and it presents more frequently in patients with Graves' disease. Muscular...

  • Beyond the Graves. Knight, Mike // Indianapolis Monthly;Nov2002, Vol. 26 Issue 3, p116 

    Focuses on the chronic condition of the eyes called the Graves' disease suffered by the author and the psychological effect it had on the author. Description of the disease; Diagnosis of the author's condition by the doctor; Change in the author's lifestyle due to the disease.

  • Had your eyes checked lately? Edry, Sharon // Self;Mar2001, Vol. 23 Issue 3, p98 

    Focuses on some eye health problems. Information on Graves' disease; Cause of extreme redness and swelling of the eye; Indications of yellow streaks on the eyelids.

  • Hypothyroidism Presenting as Hoffman's Syndrome - A Case Report. NEKI, N. S.; SINGH, ISHU; KUMAR, JASBIR; JAIN, ANKUR; MANI, TAMIL // Journal of Medicine;2015, Vol. 16 Issue 2, p112 

    Hoffman syndrome is characterized by pseudohypertrophy of muscles, muscle's weakness & stiffness complicating hypothyroidism. We describe the disorder in a 45 years old female admitted with complaints of myalgia, proximal muscle weakness & calf muscle hypertrophy since 11 months. Thyroid...

  • Delayed Graves' Ophthalmopathy. Nebesio, Todd D.; Eugster, Erica A. // New England Journal of Medicine;5/6/2010, Vol. 362 Issue 18, pe60 

    The article describes the clinical care of an 18-year-old man who developed delayed Graves' ophthalmopathy.

  • Graves' ophthalmopathy: diagnosis and management. Prummel, Mark F. // European Journal of Nuclear Medicine;2000, Vol. 27 Issue 4, p373 

    Discusses the diagnosis and treatment of ophthalmopathy associated with Graves' hyperthyroidism. Symptoms of Graves' ophthalmopathy; Assessment of the activity of Graves' ophthalmopathy; Performance of the octreoscan or octreotide scanning in ophthalmopathy; Management of Graves' ophthalmopathy.

  • 2001-An Ocular Odyssey: Lessons Learned from 25 Years of Surgical Treatment for Graves Eye Disease. Del Monte, Monte A. // American Orthoptic Journal;2002, Vol. 52, p40 

    Presents a study on surgical treatment of graves eye disease. Methods; Surgical results; Conclusion.

  • Treatment of Neonatal Graves' Disease with Sodium Ipodate. Joshi, Renu; Kulin, Howard E. // Clinical Pediatrics;Mar1993, Vol. 32 Issue 3, p181 

    This article focuses on treatment of neonatal Graves' Disease with Sodium Ipodate. Graves' disease is a relatively common endocrinopathy during pregnancy, appearing in 1 of 1,000 women with otherwise normal gestations. Approximately 1 of 70 neonates born to mothers with a history of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics