TITLE

Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series

PUB. DATE
January 2011
SOURCE
Journal of Medical Case Reports;2011, Vol. 5 Issue 1, p296
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
The article presents a series of clinical case reports demonstrating regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis. Case reports of all the patients revealed that a combination of percutaneously injected autologous adipose-tissue-derived stem cells, hyaluronic acid, platelet rich plasma and calcium chloride may be able to regenerate bones in human osteonecrosis.
ACCESSION #
65284632

 

Related Articles

  • Researchers report good first results using blood stem cells, HA to regenerate cartilage. Trace, Robert // Orthopedics Today;Dec2009, Vol. 29 Issue 12, p44 

    The article reports on a Malaysian study which found the first evidence of hyaline cartilage regeneration using intra-articular injections of autologous peripheral blood stem cells in combination with hyaluronic acid.

  • Culture medium optimization of a new bacterial extracellular polysaccharide with excellent moisture retention activity. Zhao, Li; Fan, Fang; Wang, Peng; Jiang, Xiaolu // Applied Microbiology & Biotechnology;Apr2013, Vol. 97 Issue 7, p2841 

    A new kind of extracellular polysaccharide (EPS) from Pseudomonas fluorescens PGM37 was obtained and culture media was optimized using the statistical methods single factor experiments and response surface methodology (RSM) design. As a result, the optimum cultivation conditions initial pH...

  • Hyaluronidase recruits mesenchymal-like cells to the lung and ameliorates fibrosis. Bitencourt, Claudia S.; Pereira, Priscilla A. T.; Ramos, Simone G.; Sampaio, Suely V.; Arantes, Eliane C.; Aronoff, David M.; Faccioli, L�cia H. // Fibrogenesis & Tissue Repair;2011, Vol. 4 Issue 1, p3 

    Hyaluronidases (HYALs) comprise a group of enzymes that degrade hyaluronic acid (HA). In this report, we reveal that a single intranasal inoculation of HYAL induces an increase in mononuclear cells within the bronchoalveolar space demonstrating a mesenchymal-like phenotype, expressing stem cell...

  • Acceleration of Wound Healing with Stem Cell-Derived Growth Factors. Tamari, Masayuki; Nishino, Yudai; Yamamoto, Noriyuki; Ueda, Minoru // Oral & Craniofacial Tissue Engineering;2011, Vol. 1 Issue 3, p181 

    Purpose: Recently, it has been revealed that bone marrow-derived mesenchymal stem cells (MSCs) accelerate the healing of skin wounds. Although the proliferative capacity of MSCs decreases with age, MSCs secrete many growth factors. The present study examined the effect of mesenchymal stem...

  • A fibrin/hyaluronic acid hydrogel for the delivery of mesenchymal stem cells and potential for articular cartilage repair. Snyder, Timothy N.; Madhavan, Krishna; Intrator, Miranda; Dregalla, Ryan C.; Daewon Park // Journal of Biological Engineering;2014, Vol. 8 Issue 1, p1 

    Background Osteoarthritis (OA) is a degenerative joint disease affecting approximately 27 million Americans, and even more worldwide. OA is characterized by degeneration of subchondral bone and articular cartilage. In this study, a chondrogenic fibrin/hyaluronic acid (HA)-based hydrogel seeded...

  • CD44 and hyaluronan help mesenchymal stem cells move to a neighborhood in need of regeneration. Poulsom, R. // Kidney International;Aug2007, Vol. 72 Issue 4, p389 

    Prevention of normal interactions between CD44 cell-surface receptors on cultured mesenchymal stem cells and hyaluronic acid in the renal interstitial matrix has been described as reducing the ability of these cells in vivo to localize to regions with acute tubular injury. Understanding...

  • Mechanical Response of Porous Scaffolds for Cartilage Engineering. Jančář, J.; Slovíková, A.; Amler, E.; Krupa, P.; Kecová, H.; Plánka, L.; Gál, P.; Nečas, A. // Physiological Research;2007 Supplement 1, Vol. 56, pS17 

    Mechanical properties of scaffolds seeded with mesenchymal stem cells used for cartilage repair seem to be one of the critical factors in possible joint resurfacing. In this paper, the effect of adding hyaluronic acid, hydroxyapatite nanoparticles or chitosan nanofibers into the cross-linked...

  • Microrna: Micromanaging CD44. McCarthy, Nicola // Nature Reviews Cancer;Mar2011, Vol. 11 Issue 3, p156 

    The article cites a research study by Dean Tang and colleagues that analyzed CD44, a receptor for hyaluronan, as a marker of cancer stem cells (CSCs). The authors determined the requirement of CD44 for CSC function in prostate cancer by establishing that CD44 is a target of the microRNA miR.34a....

  • Hyaluronan substratum holds mesenchymal stem cells in slow-cycling mode by prolonging G1 phase. Chi-Mou Liu; Chen-Hsiang Yu; Chiung-Hsin Chang; Chao-Chin Hsu; Huang, Lynn L. H. // Cell & Tissue Research;Feb2009, Vol. 334 Issue 3, p435 

    We examined, in vitro, whether hyaluronan induces slow cycling in placenta-derived mesenchymal stem cells (PDMSCs) by comparing cell growth on a hyaluronan-coated surface with cell growth on a tissue-culture polystyrene surface. The hyaluronan-coated surface significantly downregulated the...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics