Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series
- Researchers report good first results using blood stem cells, HA to regenerate cartilage. Trace, Robert // Orthopedics Today;Dec2009, Vol. 29 Issue 12, p44
The article reports on a Malaysian study which found the first evidence of hyaline cartilage regeneration using intra-articular injections of autologous peripheral blood stem cells in combination with hyaluronic acid.
- Culture medium optimization of a new bacterial extracellular polysaccharide with excellent moisture retention activity. Zhao, Li; Fan, Fang; Wang, Peng; Jiang, Xiaolu // Applied Microbiology & Biotechnology;Apr2013, Vol. 97 Issue 7, p2841
A new kind of extracellular polysaccharide (EPS) from Pseudomonas fluorescens PGM37 was obtained and culture media was optimized using the statistical methods single factor experiments and response surface methodology (RSM) design. As a result, the optimum cultivation conditions initial pH...
- Hope for arthritics. // Asian Pacific Post;6/7/2012, p13
This article reports that doctors at Southampton General Hospital in Hampshire, England pioneered a new stem cell procedure that tackle osteonecrosis, a bone disease that leads to arthritis.
- Comment on: Osteogenic abilities of bone marrow stromal cells are not defective in patients with osteonecrosis. Gao, You-Shui; Zhang, Chang-Qing // International Orthopaedics;Mar2010, Vol. 34 Issue 3, p457
A letter to the editor is presented in response to the article "Osteogenic Abilities of Bone Marrow Stromal Cells Are Not Defective in Patients With Osteonecrosis," by J. J. Yoo et al.
- Reply to the comments on our article 'Osteogenic abilities of bone marrow stromal cells are not defective in patients with osteonecrosis'. Kim, Hee // International Orthopaedics;Mar2010, Vol. 34 Issue 3, p459
A response by Hee Joong Kim to a letter to the editor about the article "Osteogenic Abilities of Bone Marrow Stromal Cells Are Not Defective in Patients With Osteonecrosis" that was published in 2009 is presented.
- The effect of combined regulation of the expression of peroxisome proliferator-activated receptor-Î³ and calcitonin gene-related peptide on alcohol-induced adipogenic differentiation of bone marrow mesenchymal stem cells. Li, Jinfeng; Wang, Yisheng; Li, Yuebai; Sun, Junkui; Zhao, Guoqiang // Molecular & Cellular Biochemistry;Jul2014, Vol. 392 Issue 1/2, p39
Studies have shown that alcohol can upregulate the expression of peroxisome proliferator-activated receptor-Î³ (PPARÎ³) gene in bone marrow mesenchymal stem cells (BMSCs). High expression of PPARÎ³ can promote adipogenic differentiation of BMSCs, and reduce their osteogenic...
- Microrna: Micromanaging CD44. McCarthy, Nicola // Nature Reviews Cancer;Mar2011, Vol. 11 Issue 3, p156
The article cites a research study by Dean Tang and colleagues that analyzed CD44, a receptor for hyaluronan, as a marker of cancer stem cells (CSCs). The authors determined the requirement of CD44 for CSC function in prostate cancer by establishing that CD44 is a target of the microRNA miR.34a....
- Hyaluronidase recruits mesenchymal-like cells to the lung and ameliorates fibrosis. Bitencourt, Claudia S.; Pereira, Priscilla A. T.; Ramos, Simone G.; Sampaio, Suely V.; Arantes, Eliane C.; Aronoff, David M.; Faccioli, L�cia H. // Fibrogenesis & Tissue Repair;2011, Vol. 4 Issue 1, p3
Hyaluronidases (HYALs) comprise a group of enzymes that degrade hyaluronic acid (HA). In this report, we reveal that a single intranasal inoculation of HYAL induces an increase in mononuclear cells within the bronchoalveolar space demonstrating a mesenchymal-like phenotype, expressing stem cell...
- Acceleration of Wound Healing with Stem Cell-Derived Growth Factors. Tamari, Masayuki; Nishino, Yudai; Yamamoto, Noriyuki; Ueda, Minoru // Oral & Craniofacial Tissue Engineering;2011, Vol. 1 Issue 3, p181
Purpose: Recently, it has been revealed that bone marrow-derived mesenchymal stem cells (MSCs) accelerate the healing of skin wounds. Although the proliferative capacity of MSCs decreases with age, MSCs secrete many growth factors. The present study examined the effect of mesenchymal stem...