Tectonic corneal graft for conjunctival rhinosporidiosis with scleral melt

Jacob, Pushpa; Rose, Jeyanth S.; Hoshing, Abhishek; Chacko, Geeta
May 2011
Indian Journal of Ophthalmology;May2011, Vol. 59 Issue 3, p251
Academic Journal
Case Study
A 16 year old girl presented with irritation and watering of the right eye for 3 months. On examination, the superior perilimbal sclera was ectatic with incarcerated uveal tissue covered by conjunctiva. The conjunctiva showed discreet, yellow white mucoid spots. Excision biopsy of the conjunctiva showed subepithelial spherules of sporangia containing numerous endospores, suggestive of rhinosporidiosis. Diathermy was applied to flatten the staphyloma. The ectatic area was covered with a corneal patch graft. The patient was started on prednisolone acetate eye drops and oral dapsone for 6 months. Corneal graft was well incorporated and conjunctivalized by 3 months. Since the graft was not seen within the palpebral aperture, there was good cosmetic result. The corneal graft had the added advantage of transparency which allowed visualization of the underlying tissue to diagnose early recurrence. There was no recurrence at 6 months.


Related Articles

  • Dapsone/dorzolamide/timolol.  // Reactions Weekly;12/11/2010, Issue 1331, p14 

    The article describes the case of a 63-year-old woman who acquired skin eruptions and thrombocytopenia while undergoing treatment with dapsone, dorzolamide and timolol.

  • Does dapsone reduce the need for steroids? Guttman, Cheryl // Dermatology Times;Sep97, Vol. 18 Issue 9, p34 

    Investigates the efficacy of dapsone as a steroid-sparing agent in patients with pemphigus vulgaris. Primary measure of dapsone efficacy; Account on the trials and other outcome variables for dapsone; Problem encountered in evaluating drug therapy on patients with pemphigus vulgaris.

  • Topical dapsone may expand acne Tx options. Wickware, Potter // Dermatology Times;Sep2000 Supplement 4, Vol. 21 Issue 9, pS16 

    Focuses on the possible efficacy of a topical dapsone preparation for treating acne. Dual antibacterial and anti-inflammatory action of the drug; Two stage delivery system for topical dapsone.

  • Topical dapsone gel offers dual mode of action in phase III studies. Guttman, Cheryl // Dermatology Times;Nov2001, Vol. 22 Issue 11, p22 

    Reports the efficacy of dapsone gel in treating acne in the United States. Possession of antibacterial activity against Propionibacterium acnes; Improvement in the presence of inflammatory lesions; Solubility in the aqueous solvents.

  • Dapsone.  // Reactions Weekly;6/5/2010, Issue 1304, p14 

    The article describes the case of a 35-year-old woman who acquired dapsone hypersensitivity syndrome while undergoing treatment with dapsone.

  • Dapsone.  // Reactions Weekly;4/24/2010, Issue 1298, p14 

    The article describes the case of 6 patients who acquired drug hypersensitivity syndrome while undergoing dapsone therapy.

  • Constructing Fluorogenic Bacillus Spores (F-Spores) via Hydrophobic Decoration of Coat Proteins. Ferencko, Linda; Rotman, Boris // PLoS ONE;2010, Vol. 5 Issue 2, p1 

    Background: Bacterial spores are protected by a coat consisting of about 60 different proteins assembled as a biochemically complex structure with intriguing morphological and mechanical properties. Historically, the coat has been considered a static structure providing rigidity and mainly...

  • A case of SLE with acute, subacute and chronic cutaneous lesions successfully treated with Dapsone. Neri, R.; Mosca, M.; Bernacchi, E.; Bombardieri, S. // Lupus;1999, Vol. 8 Issue 3, p240 

    We describe a patient with systemic lupus erythematosus (SLE) who exhibited severe cutaneous involvement characterized by the simultaneous presence of acute, subacute and discoid lesions in association with anti-Sl antibodies. After she failed to respond to chloroquine, medium to low dose...

  • Dapsone/lidocaine.  // Reactions Weekly;8/14/2010, Issue 1314, p16 

    The article describes the case of a 65-year-old woman who developed methaemoglobinaemia while undergoing treatment with dapsone and lidocaine.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics