Two Cases of Human Plague -- Oregon, 2010

Wilkie, M.; McGivern, T.; Skeels, M.; DeBess, E.; Progulske, B. A.; Cieslak, P. R.; Brouillard, K.; Gage, K. L.; Griffith, K.; Petersen, J. M.; Tourdjman, M.
February 2011
MMWR: Morbidity & Mortality Weekly Report;2/25/2011, Vol. 60 Issue 7, p214
Case Study
The article describes cases of Yersinia (Y.) pestis infections in two persons living in the same household in Oregon. Gram negative rod isolate from the patients' blood was misidentified by four clinical laboratories using commercial automated systems, which was later identified as Y. pestis by direct fluorescent F1 antigen. The patients' pet dog was also found seropositive for Y. pestis. After empiric therapy with doxycycline, both patients recovered. The cases suggest that automated bacterial identification system can misidentify Y. pestis.


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