TITLE

Suppurative dacroadenitis causing ocular sicca syndrome in classic Wegener's granulomatosis

AUTHOR(S)
Khanna, Dhanita; Shrivastava, Arun
PUB. DATE
March 2011
SOURCE
Indian Journal of Ophthalmology;Mar2011, Vol. 59 Issue 2, p151
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
Wegener's granulomatosis (WG) is a multisystem vasculitic disorder which can commonly afflict various components of the eye. Here we describe some unusual ocular manifestations of the disease in one patient. A young male with history of upper respiratory tract symptoms including epistaxis, nasal stuffiness and maxillary sinus pain presented with bilateral lacrimal gland abscess and ptosis. Lacrimal gland biopsy revealed granulomatous vasculitis. Lung cavities, positive cytoplasmicantineutrophil cytoplasmic antibodies and high titers of serine proteinase-3 antibodies confirmed the diagnosis of WG. The patient developed dry eyes after a month of first presentation. There was no dryness of mouth, suggesting the absence of salivary gland involvement, and antinuclear antibodies as well as antibodies against Ro and La antigens classical of primary Sjogren's syndrome were absent. Granulomatous vasculitis of lacrimal gland leading to abscess formation and dryness of eyes has not been described in WG and reflects the aggressive nature of inflammatory process in this disease.
ACCESSION #
59247259

 

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